Rv3549c

Tuberculist information
Gene nameRv3549c
Protein functionProbable short-chain type dehydrogenase/reductase
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)3988.32
Molecular mass(da)26823.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 259
	  		  	1    VTLAEAADAINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHR   60
			  	61   CDIRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLV  120
			  	121  SQHANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVN  180
			  	181  AVVVGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATL  240
			  	241  EVHGGGEPPPYLGASSANK

Known structures in the PDB
No Known structures
1 26 51 76 101 126 151 176 201 226 251 Range: 23 to 247  |  Coverage: 86% adh_short_C2 Range: 15 to 245  |  Coverage: 88% 1 Range: 1 to 259  |  Coverage: 99% 1
Number of amino acids : 259
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
adh_short_C2PF1356123-247
Mtb Structural Proteome models
Model Number1
Model nameRv3549c
Template2D1Y    APDBCREDO
Template coverage5_244
Template Identity(%)41.6
Model coverage(%)88.8
Normalized DOPE score-0.719

Structure Models from Chopin
Model Number1
Profilec.2.1.2 - 3.40.50.720
Click for model details
zscore24.17
Residue begin1
Residue end259
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3549cGene nameConfidence Score
Rv3552Rv35520.904
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions