Rv3548c

Tuberculist information
Gene nameRv3548c
Protein functionProbable short-chain type dehydrogenase/reductase
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)3987.38
Molecular mass(da)31070.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 304
	  		  	1    MGLVDGRVVIVTGAGGGIGRAHALAFAAEGARVVVNDIGVGLDGSPASGGSAAQDVVDEI   60
			  	61   LAAGGQAVADGSDISDWDQAANLIQAAVETYGGVDVLVNNAGIVRDRMIANTSEEEFDAV  120
			  	121  IAVHLKGHFATMRHAASHWRGLSKAGKAPKDIDARIINTSSGAGLQGSVGQGNYSAAKAG  180
			  	181  IAALTLVGAAEMRRYGVTVNAIAPAARTRMTETVFAEMMAKPQEGFDAMAPENVSPLVVW  240
			  	241  LGSAESRDVTGKVFEVEGGIIRVAEGWAHGPQVDKGVKWDPAELGPVVSDLLAKSRPPVP  300
			  	301  VYGA

Known structures in the PDB
No Known structures
1 31 61 91 121 151 181 211 241 271 301 Range: 7 to 193  |  Coverage: 61% adh_short Range: 3 to 300  |  Coverage: 97% 1 Range: 1 to 304  |  Coverage: 99% 1
Number of amino acids : 304
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
adh_shortPF001067-193
Mtb Structural Proteome models
Model Number1
Model nameRv3548c
Template1ZBQ    APDBCREDO
Template coverage6_266
Template Identity(%)45.2
Model coverage(%)97.7
Normalized DOPE score0.191

Structure Models from Chopin
Model Number1
Profilec.2.1.2 - 3.40.50.720
Click for model details
zscore17.07
Residue begin1
Residue end304
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3548cGene nameConfidence Score
Rv3552Rv35520.916
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions