Rv3530c

Tuberculist information
Gene nameRv3530c
Protein functionPossible oxidoreductase
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)3967.04
Molecular mass(da)27757.6
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 260
	  		  	1    MTGMLKRKVIVVSGVGPGLGTTLAHRCARDGADLVLAARSAERLDDVAKQIIDTGRRAVA   60
			  	61   VRTDITDDDDVSNLVQATLAAYGKADVLINNAFRVPSMKPLAGTTFEHIRDAIELSALGT  120
			  	121  LRLIQAFTPALAQSHGAIVNVNSMVIRHSQPKYGTYKMAKSVLLAMSHSLATELGEQGIR  180
			  	181  VNSVAPGYIWGDTLKSYFDHQAGKYGTTVDQIYQATAANSDLKRLPTEDEVASAILFLAS  240
			  	241  DLASGITGQTLDVNCGEYHT

Known structures in the PDB
No Known structures
1 27 53 79 105 131 157 183 209 235 261 Range: 14 to 257  |  Coverage: 93% adh_short_C2 Range: 2 to 260  |  Coverage: 99% 1 Range: 1 to 260  |  Coverage: 99% 1
Number of amino acids : 260
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
adh_short_C2PF1356114-257
Mtb Structural Proteome models
Model Number1
Model nameRv3530c
Template2BGK    APDBCREDO
Template coverage11_265
Template Identity(%)31.4
Model coverage(%)99.2
Normalized DOPE score-0.172

Structure Models from Chopin
Model Number1
Profilec.2.1.2 - 3.40.50.720
Click for model details
zscore25.54
Residue begin1
Residue end260
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3530cGene nameConfidence Score
Rv3531cRv3531c0.993
Rv3529cRv3529c0.908
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
NAD+PubChem0.933663.425
catecholPubChem0.902110.111
dihydronicotinamide formycin dinucleotidePubChem0.9665.441
reduced nicotinamide adenine dinucleotidePubChem0.9665.441
carbon dioxidePubChem0.944.0095