Rv3480c

Tuberculist information
Gene nameRv3480c
Protein functionPossible triacylglycerol synthase (diacylglycerol acyltransferase)
Functional category(tuberculist)lipid metabolism
Gene location(kb)3898.91
Molecular mass(da)53282.5
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 497
	  		  	1    VSQTARRLGPQDMFFLYSESSTTMMHVGALMPFTPPSGAPPDLLRQLVDESKASEVVEPW   60
			  	61   SLRLSHPELLYHPTQSWVVDDNFDLDYHVRRSALASPGDERELGIPVSRLHSHALDLRRP  120
			  	121  PWEVHFIEGLEGGRFAIYIKMHHSLIDGYTGQKMLARSLSTDPHDTTHPLFFNIPTPGRS  180
			  	181  PADTQDSVGGGLIAGAGNVLDGLGDVVRGLGGLVSGVGSVLGSVAGAGRSTFELTKALVN  240
			  	241  AQLRSDHEYRNLVGSVQAPHCILNTRISRNRRFATQQYPLDRLKAIGAQYDATINDVALA  300
			  	301  IIGGGLRRFLDELGELPNKSLIVVLPVNVRPKDDEGGGNAVATILATLGTDVADPVQRLA  360
			  	361  AVTASTRAAKAQLRSMDKDAILAYSAALMAPYGVQLASTLSGVKPPWPYTFNLCVSNVPG  420
			  	421  PEDVLYLRGSRMEASYPVSLVAHSQALNVTLQSYAGTLNFGFIGCRDTLPHLQRLAVYTG  480
			  	481  EALDQLAAADGAAGLGS

Known structures in the PDB
No Known structures
1 50 99 148 197 246 295 344 393 442 491 Range: 8 to 298  |  Coverage: 58% WES_acyltransf Range: 320 to 489  |  Coverage: 34% DUF1298 Range: 8 to 488  |  Coverage: 96% 1 Range: 1 to 197  |  Coverage: 39% 1
Number of amino acids : 497
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
WES_acyltransfPF030078-298
DUF1298PF06974320-489
Mtb Structural Proteome models
Model Number1
Model nameRv3480c
Template1L5A    APDBCREDO
Template coverage1_406
Template Identity(%)14.0
Model coverage(%)96.6
Normalized DOPE score0.906

Structure Models from Chopin
Model Number1
Profilec.43.1.2
Click for model details
zscore4.72
Residue begin1
Residue end197
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3480cGene nameConfidence Score
Rv1543Rv15430.919
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions