Rv3394c

Tuberculist information
Gene nameRv3394c
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)3809.44
Molecular mass(da)56634.6
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 527
	  		  	1    VMASARVLAIWCMDWPAVAAAAAAGLSATAPVAVTLANRVIACSATARAAGVRRGLRRRE   60
			  	61   AAARCPQLFIATADADRDARLFEGVIAAVDDLVPRAELLRPGLLVLPVRGPARFFGSEQM  120
			  	121  AAERLIDAVAAAGAECQVGIADRLSTAVFAARAGRIVEPGGDARFLSLLSIRQLATEPSL  180
			  	181  SGPGRDDLTDLLWRMGIRTIGQFAALSRTDVASRFGADAVAAHRFARGEPERAPCGREPP  240
			  	241  PDLAAELACDPPIDRVDAAAFAGRSLAAELHRALMAAGVGCTRLAIHAVTANGEERSRVW  300
			  	301  RCAEPLTEDATADRVRWQLDGWLNNRNARDRPTAAVTLLRLQAVETVSASEGLQLPLWGG  360
			  	361  LGEQDRLRARRALVRVQGLLGPEAVRVPVLSGGHGPAERITLTVLGLVAPEPVPQADPGQ  420
			  	421  PWPGRLPDPSPAVLFDDPVDLLDAQGNPIRVTSRGMFSADPARLRVRGRDDRLRWWAGPW  480
			  	481  PDDERWWDPDRASGRTARAQVLLDGDPGTALLLCYRQRRWYLEGSYE

Known structures in the PDB
No Known structures
1 53 105 157 209 261 313 365 417 469 521 Range: 13 to 152  |  Coverage: 26% IMS Range: 209 to 339  |  Coverage: 24% IMS_C Range: 3 to 348  |  Coverage: 65% 1 Range: 13 to 152  |  Coverage: 26% 1 Range: 2 to 347  |  Coverage: 65% 2 Range: 1 to 240  |  Coverage: 45% 3 Range: 240 to 351  |  Coverage: 21% 4
Number of amino acids : 527
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
IMSPF0081713-152
IMS_CPF11799209-339
Mtb Structural Proteome models
Model Number1
Model nameRv3394c
Template2AQ4    APDBCREDO
Template coverage354_737
Template Identity(%)13.6
Model coverage(%)65.5
Normalized DOPE score1.042

Structure Models from Chopin
Model Number1
Profilee.8.1.7
Click for model details
zscore32.07
Residue begin13
Residue end152
Model Number2
Profile1.10.150.20, 3.30.1490.100, 3.30.70.270
Click for model details
zscore21.71
Residue begin2
Residue end347
Model Number3
Profilee.8.1.7
Click for model details
zscore10.15
Residue begin1
Residue end240
Model Number4
Profile3.30.1490.100
Click for model details
zscore10.11
Residue begin240
Residue end351
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3394cGene nameConfidence Score
Rv3395cRv3395c0.996
Rv3370cdnaE20.98
Rv3370cdnaE20.98
Rv3370cdnaE20.98
Rv3370cdnaE20.98
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions