Rv3371

Tuberculist information
Gene nameRv3371
Protein functionPossible triacylglycerol synthase (diacylglycerol acyltransferase)
Functional category(tuberculist)lipid metabolism
Gene location(kb)3784.93
Molecular mass(da)48847.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 446
	  		  	1    MAQLTALDAGFLKSRDPERHPGLAIGAVAVVNGAAPSYDQLKTVLTERIKSIPRCTQVLA   60
			  	61   TEWIDYPGFDLTQHVRRVALPRPGDEAELFRAIALALERPLDPDRPLWECWIIEGLNGNR  120
			  	121  WAILIKIHHCMAGAMSAAHLLARLCDDADGSAFANNVDIKQIPPYGDARSWAETLWRMSV  180
			  	181  SIAGAVCTAAARAVSWPAVTSPAGPVTTRRRYQAVRVPRDAVDAVCHKFGVTANDVALAA  240
			  	241  ITEGFRTVLLHRGQQPRADSLRTLEKTDGSSAMLPYLPVEYDDPVRRLRTVHNRSQQSGR  300
			  	301  RQPDSLSDYTPLMLCAKMIHALARLPQQGIVTLATSAPRPRHQLRLMGQKMDQVLPIPPT  360
			  	361  ALQLSTGIAVLSYGDELVFGITADYDAASEMQQLVNGIELGVARLVALSDDSVLLFTKDR  420
			  	421  RKRSSRALPSAARRGRPSVPTARARH

Known structures in the PDB
No Known structures
1 45 89 133 177 221 265 309 353 397 441 Range: 23 to 391  |  Coverage: 82% AATase Range: 7 to 426  |  Coverage: 93% 1 Range: 1 to 183  |  Coverage: 40% 1
Number of amino acids : 446
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
AATasePF0724723-391
Mtb Structural Proteome models
Model Number1
Model nameRv3371
Template1L5A    APDBCREDO
Template coverage4_421
Template Identity(%)12.7
Model coverage(%)93.9
Normalized DOPE score0.841

Structure Models from Chopin
Model Number1
Profilec.43.1.2
Click for model details
zscore4.54
Residue begin1
Residue end183
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3371Gene nameConfidence Score
Rv1543Rv15430.926
Rv3391acrA10.918
Rv3391acrA10.918
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions