Rv3359

Tuberculist information
Gene nameRv3359
Protein functionPossible oxidoreductase
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)3771.34
Molecular mass(da)42803.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 396
	  		  	1    VAPGSCEAPDVFNPAKLGPLTLRNRVIKAATFEARTPDALVTDDLIEYHRLPAAGGVAMT   60
			  	61   TVAYCAVSPGGRTGGNQIWMRPHAVPGLRRLTEAIHAEGAAISAQIGHAGPVADARSNQA  120
			  	121  TALAPVRFFNPIAMRFAQKATREDIDDVLAAHAHAARLAVDAGFDAVEIHLGHNYLASAF  180
			  	181  LSPLLNRRDDEFGGSLQNRAKVARGLVMAVRRAVRQQVAVTAKLNMTDGIRGGITVDEAL  240
			  	241  TTARWLQDDGGLDAIELTAGSSLVNPMYLFRGDAPVKEFAAAFKPPLRWGIRMTGHRFFR  300
			  	301  EYPYRDAYLLREARLFRAELTIPLILLGGITNRTTMDLAMAEGFEFVAMARALLAEPDLV  360
			  	361  NRIAAEGSQVRSACTHCNQCMATIYRRTHCVVTGAP

Known structures in the PDB
No Known structures
1 40 79 118 157 196 235 274 313 352 391 Range: 10 to 267  |  Coverage: 64% Oxidored_FMN Range: 295 to 369  |  Coverage: 18% Oxidored_FMN Range: 9 to 394  |  Coverage: 97% 1 Range: 304 to 393  |  Coverage: 22% 1
Number of amino acids : 396
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Oxidored_FMNPF0072410-267
Oxidored_FMNPF00724295-369
Mtb Structural Proteome models
Model Number1
Model nameRv3359
Template1PS9    APDBCREDO
Template coverage3_357
Template Identity(%)27.6
Model coverage(%)97.2
Normalized DOPE score0.477

Structure Models from Chopin
Model Number1
Profilec.1.31.1 - 3.20.20.70
Click for model details
zscore10.98
Residue begin304
Residue end393
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3359Gene nameConfidence Score
Rv3355cRv3355c0.941
Rv3356cfolD0.914
Rv3356cfolD0.914
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
flavin mononucleotidePubChem0.812456.344