Rv3302c

Tuberculist information
Gene nameglpD2
Protein functionProbable glycerol-3-phosphate dehydrogenase GlpD2
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)3687.69
Molecular mass(da)62745.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 585
	  		  	1    VSNPIQAPDGGQGWPAAALGPAQRAVAWKRLGTEQFDVVVIGGGVVGSGCALDAATRGLK   60
			  	61   VALVEARDLASGTSSRSSKMFHGGLRYLEQLEFGLVREALYERELSLTTLAPHLVKPLPF  120
			  	121  LFPLTKRWWERPYIAAGIFLYDRLGGAKSVPAQRHFTRAGALRLSPGLKRSSLIGGIRYY  180
			  	181  DTVVDDARHTMTVARTAAHYGAVVRCSTQVVALLREGDRVIGVGVRDSENGAVAEVRGHV  240
			  	241  VVNATGVWTDEIQALSKQRGRFQVRASKGVHVVVPRDRIVSDVAMILRTEKSVMFVIPWG  300
			  	301  SHWIIGTTDTDWNLDLAHPAATKADIDYILGTVNAVLATPLTHADIDGVYAGLRPLLAGE  360
			  	361  SDDTSKLSREHAVAVPAAGLVAIAGGKYTTYRVMAADAIDAAVQFIPARVAPSITEKVSL  420
			  	421  LGADGYFALVNQAEHVGALQGLHPYRVRHLLDRYGSLISDVLAMAASDPSLLSPITEAPG  480
			  	481  YLKVEAAYAAAAEGALHLEDILARRMRISIEYPHRGVDCAREVAEVVAPVLGWTAADIDR  540
			  	541  EVANYMARVEAEVLSQAQPDDVSADMLRASAPEARAEILEPVPLD

Known structures in the PDB
No Known structures
1 59 117 175 233 291 349 407 465 523 581 Range: 37 to 392  |  Coverage: 60% DAO Range: 30 to 576  |  Coverage: 93% 1 Range: 34 to 241  |  Coverage: 35% 1
Number of amino acids : 585
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
DAOPF0126637-392
Mtb Structural Proteome models
Model Number1
Model nameRv3302c
Template2H88    APDBCREDO
Template coverage13_553
Template Identity(%)13.9
Model coverage(%)93.2
Normalized DOPE score0.974

Structure Models from Chopin
Model Number1
Profilec.3.1.7
Click for model details
zscore5.72
Residue begin34
Residue end241
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3302cGene nameConfidence Score
Rv3696cglpK0.989
Rv3696cglpK0.989
Rv3301cphoY10.933
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
glycerol-3-phosphatePubChem0.978172.074
dihydroxyacetone phosphatePubChem0.974170.058
CoQPubChem0.913318.407
glycerol 1-phosphatePubChem0.9172.074
2,3-dimethoxy-5-methyl-6-(3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaenylPubChem0.9731.141
2,3-dimethoxy-5-methyl-6-[(2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,PubChem0.9731.141
ubiquinone-8PubChem0.9727.109
glycerolPubChem0.81492.0938
flavin adenine dinucleotidePubChem0.746785.55