Rv3200c

Tuberculist information
Gene nameRv3200c
Protein functionPossible transmembrane cation transporter
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)3572.6
Molecular mass(da)38099.9
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 355
	  		  	1    VAGSWRRLRGLNEKLTAQPGYALVGVLRIPQRRASPARVISRRVVVAVVALLLTAGIVYV   60
			  	61   DRDGYLDAQGDRLTFLDCLYYAAVTLSTTGYGDITPISEFARAINIFVITPLRIAFLILL  120
			  	121  VGTTLEVLTETSRQAYKIQRWRSRVRNHTVVIGYGTKGKTAVAAMVSDELVPGEIVVVDT  180
			  	181  DSGVLERAAAAGLVTVHGDATKSDVLRLAGTQHASSIIVATSRDDTAVLVTLTAREIAPK  240
			  	241  AKIVASIREAENQHLLRQSGADTVVVSSETAGRLLGIATTTPSVVEMIEDLLTPEAGLAV  300
			  	301  AEREVEQAEVGGSPRHLRDIVLGVVRDGQLLRIGAPEVDAIEASDRLLYIRQVGR

Known structures in the PDB
No Known structures
1 36 71 106 141 176 211 246 281 316 351 Range: 45 to 130  |  Coverage: 23% Ion_trans_2 Range: 149 to 267  |  Coverage: 33% TrkA_N Range: 51 to 350  |  Coverage: 84% 1 Range: 15 to 119  |  Coverage: 29% 2 Range: 46 to 355  |  Coverage: 87% 1 Range: 145 to 295  |  Coverage: 42% 2 Range: 45 to 130  |  Coverage: 23% 3 Range: 11 to 130  |  Coverage: 33% 4
Number of amino acids : 355
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Ion_trans_2PF0788545-130
TrkA_NPF02254149-267
Mtb Structural Proteome models
Model Number1
Model nameRv3200c
Template1LNQ    APDBCREDO
Template coverage24_321
Template Identity(%)27.8
Model coverage(%)84.2
Normalized DOPE score0.987

Model Number2
Model nameRv3200c.1
Template1ORQ    CPDBCREDO
Template coverage113_227
Template Identity(%)23.8
Model coverage(%)29.3
Normalized DOPE score1.081

Structure Models from Chopin
Model Number1
Profilec.2.1.9, d.286.1.1, f.14.1.1 - 1.10.287.70, 1.20.5.870, 3.30.70.1450, 3.40.50.720
Click for model details
zscore34.77
Residue begin46
Residue end355
Model Number2
Profilec.2.1.9 - 3.40.50.720
Click for model details
zscore27.14
Residue begin145
Residue end295
Model Number3
Profilef.14.1.1 - 1.10.287.70
Click for model details
zscore8.75
Residue begin45
Residue end130
Model Number4
Profilef.14.1.1
Click for model details
zscore8.39
Residue begin11
Residue end130
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3200cGene nameConfidence Score
Rv3199cnudC0.91
Rv3199cnudC0.91
Rv3199cnudC0.91
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
calciumPubChem0.74740.078