Rv3137

Tuberculist information
Gene nameRv3137
Protein functionProbable monophosphatase
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)3503.39
Molecular mass(da)27661.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 260
	  		  	1    VSHDDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRP   60
			  	61   GDGVLGEEFGGSTTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPAL  120
			  	121  QRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLTDT  180
			  	181  VWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGG  240
			  	241  SAVATNGLLHDEVLTRLNAG

Known structures in the PDB
No Known structures
1 27 53 79 105 131 157 183 209 235 261 Range: 3 to 259  |  Coverage: 98% Inositol_P Range: 2 to 258  |  Coverage: 98% 1 Range: 1 to 260  |  Coverage: 99% 1 Range: 144 to 260  |  Coverage: 44% 2
Number of amino acids : 260
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Inositol_PPF004593-259
Mtb Structural Proteome models
Model Number1
Model nameRv3137
Template1KA1    APDBCREDO
Template coverage3_349
Template Identity(%)28.8
Model coverage(%)98.5
Normalized DOPE score-0.468

Structure Models from Chopin
Model Number1
Profilee.7.1.1
Click for model details
zscore29.62
Residue begin1
Residue end260
Model Number2
Profile3.40.190.80
Click for model details
zscore11.41
Residue begin144
Residue end260
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3137Gene nameConfidence Score
Rv3138pflA0.926
Rv1082mca0.914
Rv0486mshA0.91
Rv0486mshA0.91
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
fructosePubChem0.902180.156
5-amino-2,6-dioxo-4-ribitylaminopyrimidinePubChem0.9276.247
C04454PubChem0.9356.226
thiamine monophosphatePubChem0.9345.334
D-fructosePubChem0.9180.156
5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedionePubChem0.9276.247
inositol 1-phosphatePubChem0.737260.136