Rv3117

Tuberculist information
Gene namecysA3
Protein functionProbable thiosulfate sulfurtransferase CysA3 (rhodanese-like protein) (thiosulfate cyanide transsulfurase) (thiosulfate thiotransferase)
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)3483.97
Molecular mass(da)31014.6
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 277
	  		  	1    MARCDVLVSADWAESNLHAPKVVFVEVDEDTSAYDRDHIAGAIKLDWRTDLQDPVKRDFV   60
			  	61   DAQQFSKLLSERGIANEDTVILYGGNNNWFAAYAYWYFKLYGHEKVKLLDGGRKKWELDG  120
			  	121  RPLSSDPVSRPVTSYTASPPDNTIRAFRDEVLAAINVKNLIDVRSPDEFSGKILAPAHLP  180
			  	181  QEQSQRPGHIPGAINVPWSRAANEDGTFKSDEELAKLYADAGLDNSKETIAYCRIGERSS  240
			  	241  HTWFVLRELLGHQNVKNYDGSWTEYGSLVGAPIELGS

Known structures in the PDB
No Known structures
1 28 55 82 109 136 163 190 217 244 271 Range: 9 to 119  |  Coverage: 39% Rhodanese Range: 148 to 268  |  Coverage: 43% Rhodanese
Number of amino acids : 277
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
RhodanesePF005819-119
RhodanesePF00581148-268
Mtb Structural Proteome models
Structure models not available for this query
Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
Structure models not available for this query
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3117Gene nameConfidence Score
Rv3116moeB20.976
Rv3116moeB20.976
Rv3116moeB20.976
Rv3118sseC10.963
Rv3206cmoeB10.921
Rv3206cmoeB10.921
Rv3206cmoeB10.921
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
thiosulfatePubChem0.942112.128
cyanidePubChem0.93927.0253
thiocyanatePubChem0.93159.0903
bisulfitePubChem0.91580.0632
protiumPubChem0.92.01576
H(+)PubChem0.92.01588
deuteriumPubChem0.92.01588