Rv2859c

Tuberculist information
Gene nameRv2859c
Protein functionPossible amidotransferase
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)3170.72
Molecular mass(da)32409.6
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 308
	  		  	1    VDLSASRSDGGDPLRPASPRLRSPVSDGGDPLRPASPRLRSPVSDGGDPLRPASPRLRSP   60
			  	61   LGASRPVVGLTAYLEQVRTGVWDIPAGYLPADYFEGITMAGGVAVLLPPQPVDPESVGCV  120
			  	121  LDSLHALVITGGYDLDPAAYGQEPHPATDHPRPGRDAWEFALLRGALQRGMPVLGICRGT  180
			  	181  QVLNVALGGTLHQHLPDILGHSGHRAGNGVFTRLPVHTASGTRLAELIGESADVPCYHHQ  240
			  	241  AIDQVGEGLVVSAVDVDGVIEALELPGDTFVLAVQWHPEKSLDDLRLFKALVDAASGYAG  300
			  	301  RQSQAEPR

Known structures in the PDB
No Known structures
1 31 61 91 121 151 181 211 241 271 301 Range: 66 to 279  |  Coverage: 69% Peptidase_C26 Range: 32 to 303  |  Coverage: 87% 1 Range: 25 to 308  |  Coverage: 91% 1
Number of amino acids : 308
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Peptidase_C26PF0772266-279
Mtb Structural Proteome models
Model Number1
Model nameRv2859c
Template1S1M    APDBCREDO
Template coverage251_544
Template Identity(%)17.6
Model coverage(%)88.0
Normalized DOPE score-0.214

Structure Models from Chopin
Model Number1
Profilec.23.16.1 - 3.40.50.880
Click for model details
zscore11.58
Residue begin25
Residue end308
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2859cGene nameConfidence Score
Rv2860cglnA40.972
Rv2860cglnA40.972
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions