Rv2755c

Tuberculist information
Gene namehsdS.1
Protein functionPossible type I restriction/modification system specificity determinant (fragment) HsdS.1 (S protein)
Functional category(tuberculist)information pathways
Gene location(kb)3068.19
Molecular mass(da)9475.7
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 91
	  		  	1    MSDGWKTLRFGEVLELQRGHDLPAASRGSGTVPVIGSFGVTGMHDTAAYDGPGVAIGRSG   60
			  	61   AAIGTATFVAGPIWPLDTCLFVRDFKGNDPR

Known structures in the PDB
No Known structures
1 10 19 28 37 46 55 64 73 82 91 Range: 2 to 89  |  Coverage: 95% DNA methylase specificity domain Range: 7 to 87  |  Coverage: 87% 1 Range: 1 to 91  |  Coverage: 98% 1
Number of amino acids : 91
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
DNA methylase specificity domaind.287.12-89
Mtb Structural Proteome models
Model Number1
Model nameRv2755c
Template1YDX    APDBCREDO
Template coverage203_285
Template Identity(%)18.5
Model coverage(%)87.0
Normalized DOPE score0.047

Structure Models from Chopin
Model Number1
Profiled.287.1.2
Click for model details
zscore11.25
Residue begin1
Residue end91
Binding pockets
STRING
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Protein interacting with Rv2755cGene nameConfidence Score
Rv2756chsdM0.948
Rv2756chsdM0.948
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions