Rv2752c

Tuberculist information
Gene nameRv2752c
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)3064.51
Molecular mass(da)59500.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 558
	  		  	1    VDVDLPPPGPLTSGGLRVTALGGINEIGRNMTVFEHLGRLLIIDCGVLFPGHDEPGVDLI   60
			  	61   LPDMRHVEDRLDDIEALVLTHGHEDHIGAIPFLLKLRPDIPVVGSKFTLALVAEKCREYR  120
			  	121  ITPVFVEVREGQSTRHGVFECEYFAVNHSTPDALAIAVYTGAGTILHTGDIKFDQLPPDG  180
			  	181  RPTDLPGMSRLGDTGVDLLLCDSTNAEIPGVGPSESEVGPTLHRLIRGADGRVIVACFAS  240
			  	241  NVDRVQQIIDAAVALGRRVSFVGRSMVRNMRVARQLGFLRVADSDLIDIAAAETMAPDQV  300
			  	301  VLITTGTQGEPMSALSRMSRGEHRSITLTAGDLIVLSSSLIPGNEEAVFGVIDALSKIGA  360
			  	361  RVVTNAQARVHVSGHAYAGELLFLYNGVRPRNVMPVHGTWRMLRANAKLAASTGVPQESI  420
			  	421  LLAENGVSVDLVAGKASISGAVPVGKMFVDGLIAGDVGDITLGERLILSSGFVAVTVVVR  480
			  	481  RGTGQPLAAPHLHSRGFSEDPKALEPAVRKVEAELESLVAANVTDPIRIAQGVRRTVGKW  540
			  	541  VGETYRRQPMIVPTVIEV

Known structures in the PDB
No Known structures
1 56 111 166 221 276 331 386 441 496 551 Range: 24 to 237  |  Coverage: 38% Lactamase_B Range: 365 to 401  |  Coverage: 6% RMMBL Range: 14 to 431  |  Coverage: 74% 1 Range: 11 to 544  |  Coverage: 95% 1
Number of amino acids : 558
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Lactamase_BPF0075324-237
RMMBLPF07521365-401
Mtb Structural Proteome models
Model Number1
Model nameRv2752c
Template2AZ4    APDBCREDO
Template coverage5_429
Template Identity(%)18.2
Model coverage(%)74.6
Normalized DOPE score0.401

Structure Models from Chopin
Model Number1
Profiled.157.1.10
Click for model details
zscore15.58
Residue begin11
Residue end544
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2752cGene nameConfidence Score
Rv2753cdapA0.979
Rv2783cgpsI0.931
Rv2783cgpsI0.931
Rv2783cgpsI0.931
Rv2783cgpsI0.931
Rv2783cgpsI0.931
Rv2754cthyX0.919
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
zincPubChem0.74865.409