Rv2673

Tuberculist information
Gene nameaftC
Protein functionPossible arabinofuranosyltransferase AftC
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)2989.29
Molecular mass(da)48882.7
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 433
	  		  	1    VYGALVTAADSIRTGLGASLLAGFRPRTGAPSTATILRSALWPAAVLSVLHRSIVLTTNG   60
			  	61   NITDDFKPVYRAVLNFRRGWDIYNEHFDYVDPHYLYPPGGTLLMAPFGYLPFAPSRYLFI  120
			  	121  SINTAAILVAAYLLLRMFNFTLTSVAAPALILAMFATETVTNTLVFTNINGCILLLEVLF  180
			  	181  LRWLLDGRASRQWCGGLAIGLTLVLKPLLGPLLLLPLLNRQWRALVAAVVVPVVVNVAAL  240
			  	241  PLVSDPMSFFTRTLPYILGTRDYFNSSILGNGVYFGLPTWLILFLRILFTAITFGALWLL  300
			  	301  YRYYRTGDPLFWFTTSSGVLLLWSWLVMSLAQGYYSMMLFPFLMTVVLPNSVIRNWPAWL  360
			  	361  GVYGFMTLDRWLLFNWMRWGRALEYLKITYGWSLLLIVTFTVLYFRYLDAKADNRLDGGI  420
			  	421  DPAWLTPEREGQR

Known structures in the PDB
No Known structures
1 44 87 130 173 216 259 302 345 388 431 Range: 94 to 329  |  Coverage: 54% DUF2029 Range: 131 to 429  |  Coverage: 68% 1
Number of amino acids : 433
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
DUF2029PF0959494-329
Mtb Structural Proteome models
Model Number1
Model nameRv2673
Template1XME    APDBCREDO
Template coverage11_299
Template Identity(%)18.0
Model coverage(%)68.8
Normalized DOPE score1.315

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2673Gene nameConfidence Score
Rv2181Rv21810.906
Rv3793embC0.901
Rv3793embC0.901
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions