Rv2484c

Tuberculist information
Gene nameRv2484c
Protein functionPossible triacylglycerol synthase (diacylglycerol acyltransferase)
Functional category(tuberculist)lipid metabolism
Gene location(kb)2791.02
Molecular mass(da)52309.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 491
	  		  	1    MAESGESPRLSDELGPVDYLMHRGEANPRTRSGIMALELLDGTPDWDRFRTRFENASRRV   60
			  	61   LRLRQKVVVPTLPTAAPRWVVDPDFNLDFHVRRVRVSGPATLREVLDLAEVILQSPLDIS  120
			  	121  RPLWTATLVEGMADGRAAMLLHVSHAVTDGVGGVEMFAQIYDLERDPPPRSTPPQPIPED  180
			  	181  LSPNDLMRRGINHLPIAVVGGVLDALSGAVSMAGRAVLEPVSTVSGILGYARSGIRVLNR  240
			  	241  AAEPSPLLRRRSLTTRTEAIDIRLADLHKAAKAGGGSINDAYLAGLCGALRRYHEALGVP  300
			  	301  ISTLPMAVPVNLRAEGDAAGGNQFTGVNLAAPVGTIDPVARMKKIRAQMTQRRDEPAMNI  360
			  	361  IGSIAPVLSVLPTAVLEGITGSVIGSDVQASNVPVYPGDTYLAGAKILRQYGIGPLPGVA  420
			  	421  MMVVLISRGGWCTVTVRYDRASVRNDELFAQCLQAGFDEILALAGGPAPRVLPASFDTQG  480
			  	481  AGSVPRSVSGS

Known structures in the PDB
No Known structures
1 50 99 148 197 246 295 344 393 442 491 Range: 4 to 282  |  Coverage: 56% WES_acyltransf Range: 14 to 481  |  Coverage: 95% 1 Range: 6 to 199  |  Coverage: 39% 1
Number of amino acids : 491
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
WES_acyltransfPF030074-282
Mtb Structural Proteome models
Model Number1
Model nameRv2484c
Template1L5A    APDBCREDO
Template coverage1_423
Template Identity(%)13.7
Model coverage(%)94.9
Normalized DOPE score0.503

Structure Models from Chopin
Model Number1
Profilec.43.1.2
Click for model details
zscore11.67
Residue begin6
Residue end199
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2484cGene nameConfidence Score
Rv2482cplsB20.96
Rv2483cplsC0.926
Rv2483cplsC0.926
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions