Rv2417c

Tuberculist information
Gene nameRv2417c
Protein functionConserved protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)2715.47
Molecular mass(da)28455.7
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 280
	  		  	1    VTVVVVTDTSCRLPADLREQWSIRQVPLHILLDGLDLRDGVDEIPDDIHKRHATTAGATP   60
			  	61   VELSAAYQRALADSGGDGVVAVHISSALSGTFRAAELTAAELGPAVRVIDSRSAAMGVGF  120
			  	121  AALAAGRAAAAGDELDTVARAAAAAVSRIHAFVAVARLDNLRRSGRISGAKAWLGTALAL  180
			  	181  KPLLSVDDGKLVLVQRVRTVSNATAVMIDRVCQLVGDRPAALAVHHVADPAAANDVAAAL  240
			  	241  AERLPACEPAMVTAMGPVLALHVGAGAVGVCVDVGASPPA

Known structures in the PDB
No Known structures
1 29 57 85 113 141 169 197 225 253 281 Range: 2 to 274  |  Coverage: 97% DegV Range: 2 to 272  |  Coverage: 96% 1 Range: 1 to 279  |  Coverage: 99% 1 Range: 147 to 275  |  Coverage: 45% 2
Number of amino acids : 280
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
DegVPF026452-274
Mtb Structural Proteome models
Model Number1
Model nameRv2417c
Template2G7Z    APDBCREDO
Template coverage3_276
Template Identity(%)24.2
Model coverage(%)96.4
Normalized DOPE score0.27

Structure Models from Chopin
Model Number1
Profilec.119.1.1
Click for model details
zscore47.58
Residue begin1
Residue end279
Model Number2
Profile3.30.1180.10
Click for model details
zscore26.05
Residue begin147
Residue end275
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2417cGene nameConfidence Score
Rv2974cRv2974c0.925
Rv2974cRv2974c0.925
Rv2415cRv2415c0.923
Rv2415cRv2415c0.923
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
palmitatePubChem0.818256.424
SeMetPubChem0.793196.106
selenomethioninePubChem0.793196.106
glycerolPubChem0.72892.0938
zincPubChem0.70665.409