Rv2402

Tuberculist information
Gene nameRv2402
Protein functionConserved protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)2698.53
Molecular mass(da)72734
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 642
	  		  	1    MALSSSSPLRNPFPPIADYAFLSDWETTCLISPAGSVEWLCVPRPDSPSVFGAILDRSAG   60
			  	61   HFRLGPYGVSVPSARRYLPGSLIMETTWQTHTGWLIVRDALVMGKWHDIERRSRTHRRTP  120
			  	121  MDWDAEHILLRTVRCVSGTVELMMSCEPAFDYHRLGATWEYSAEAYGEAIARANTEPDAH  180
			  	181  PTLRLTTNLRIGLEGREARARTRMKEGDDVFVALSWTKHPPPQTYDEAADKMWQTTECWR  240
			  	241  QWINIGNFPDHPWRAYLQRSALTLKGLTYSPTGALLAASTTSLPETPRGERNWDYRYAWI  300
			  	301  RDSTFALWGLYTLGLDREADDFFAFIADVSGANNNERHPLQVMYGVGGERSLVEAELHHL  360
			  	361  SGYDHARPVRIGNGAYNQRQHDIWGSILDSFYLHAKSREQVPENLWPVLKRQVEEAIKHW  420
			  	421  REPDRGIWEVRGEPQHFTSSKVMCWVALDRGAKLAERQGEKSYAQQWRAIADEIKADILE  480
			  	481  HGVDSRGVFTQRYGDEALDASLLLVVLTRFLPPDDPRVRNTVLAIADELTEDGLVLRYRV  540
			  	541  HETDDGLSGEEGTFTICSFWLVSALVEIGEVGRAKRLCERLLSFASPLLLYAEEIEPRSG  600
			  	601  RHLGNFPQAFTHLALINAVVHVIRAEEEADSSGMFQPANAPM

Known structures in the PDB
No Known structures
1 65 129 193 257 321 385 449 513 577 641 Range: 252 to 584  |  Coverage: 51% Glyco_hydro_15 Range: 4 to 632  |  Coverage: 97% 1 Range: 245 to 641  |  Coverage: 61% 1 Range: 1 to 642  |  Coverage: 99% 2
Number of amino acids : 642
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Glyco_hydro_15PF00723252-584
Mtb Structural Proteome models
Model Number1
Model nameRv2402
Template1LF6    APDBCREDO
Template coverage22_673
Template Identity(%)13.4
Model coverage(%)97.8
Normalized DOPE score0.422

Structure Models from Chopin
Model Number1
Profilea.102.1.5
Click for model details
zscore26.53
Residue begin245
Residue end641
Model Number2
Profilea.102.1.1 - 1.50.10.10
Click for model details
zscore13.07
Residue begin1
Residue end642
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2402Gene nameConfidence Score
Rv3490otsA0.94
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions