Rv2329c

Tuberculist information
Gene namenarK1
Protein functionProbable nitrite extrusion protein 1 NarK1 (nitrite facilitator 1)
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)2601.91
Molecular mass(da)55136.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 515
	  		  	1    MEQHTLLQREESPRSPAAPSLRRLGGSRHITHWDPEDLGAWEAGNKGIARRNLLWSVVTV   60
			  	61   HLGYSVWTLWPVLELLMPQDVYGFSTSDKFLLGTIATLFGAFLRMPYALASAIFGGRNWA  120
			  	121  TFSAIVLLIPAIGTTVLLTHPGLPLWPYLVCAALTGLGGGNFASSMSNANAFYPHRLKGS  180
			  	181  ALGIAGGVGNLGVPAIQLVGLLAIATVGERKPYLVCALYVVLVAIAVIGVSLFMNNVEQH  240
			  	241  RVQVNRLRPIVSAVLSTRDTWLLSLLYLGTFGSFIGFSFVFGQVLQTNFLACGQSPARAT  300
			  	301  LHAVELAFVGPLLAAVARIYGGRLADRVGGSRLTLIVFVAMTLAAGLLISASTLEGRHVG  360
			  	361  QHRGATMVGYFVCFVALFVLSGLGNGSVYKMIPTIFEACSRSLDLSEAERRDWSRIISGV  420
			  	421  VIGFVAAFGALGGVGINMALRESYLSTGSGTDAFWIFMMCYAAAAVLTWKVYDRRTVTDM  480
			  	481  GMLQAALVRQPASTPAELIGPRTQSDRFSGCSISA

Known structures in the PDB
No Known structures
1 52 103 154 205 256 307 358 409 460 511 Range: 54 to 436  |  Coverage: 74% MFS_1 Range: 34 to 484  |  Coverage: 87% 1 Range: to   |  Coverage: 0% 1 Range: to   |  Coverage: 0% 2
Number of amino acids : 515
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
MFS_1PF0769054-436
Mtb Structural Proteome models
Model Number1
Model nameRv2329c
Template1PW4    APDBCREDO
Template coverage12_447
Template Identity(%)14.2
Model coverage(%)87.2
Normalized DOPE score0.643

Structure Models from Chopin
Model Number1
Profilef.38.1.1
Click for model details
zscore10.37
Residue begin
Residue end
Model Number2
Profilef.38.1.2
Click for model details
zscore6.58
Residue begin
Residue end
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2329cGene nameConfidence Score
Rv1737cnarK20.967
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions