Rv2260

Tuberculist information
Gene nameRv2260
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)2533.33
Molecular mass(da)22137.6
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 211
	  		  	1    MAAIERVITHGTFELDGGSWEVDNNIWLVGDDSEVVVFDAAHHAAPIIDAVGGRKVVAVI   60
			  	61   CTHGHNDHVTVAPELGTALDAPVLMHPGDAVLWRMTHPDKSFRAVSDGDAVRVGGTELRA  120
			  	121  LHTPGHSPGSVCWYAPELGPGTGTVFSGDTLFAGGPGATGRSYSDFPTILRSISGRLGAL  180
			  	181  PGDTVVHTGHGDSTTIGDEIVHYEEWVARGH

Known structures in the PDB
No Known structures
1 22 43 64 85 106 127 148 169 190 211 Range: 19 to 190  |  Coverage: 81% Lactamase_B Range: 13 to 204  |  Coverage: 90% 1 Range: 3 to 211  |  Coverage: 98% 1
Number of amino acids : 211
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Lactamase_BPF0075319-190
Mtb Structural Proteome models
Model Number1
Model nameRv2260
Template1QH5    APDBCREDO
Template coverage1_187
Template Identity(%)26.7
Model coverage(%)90.5
Normalized DOPE score-0.756

Structure Models from Chopin
Model Number1
Profiled.157.1.12 - 3.60.15.10
Click for model details
zscore31.26
Residue begin3
Residue end211
Binding pockets
STRING
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Protein interacting with Rv2260Gene nameConfidence Score
Rv2259mscR0.942
Rv2259mscR0.942
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions