Rv2216

Tuberculist information
Gene nameRv2216
Protein functionConserved protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)2483.63
Molecular mass(da)31671.9
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 301
	  		  	1    MANAVVAIAGSSGLIGSALTAALRAADHTVLRIVRRAPANSEELHWNPESGEFDPHALTD   60
			  	61   VDAVVNLCGVNIAQRRWSGAFKQSLRDSRITPTEVLSAAVADAGVATLINASAVGYYGNT  120
			  	121  KDRVVDENDSAGTGFLAQLCVDWETATRPAQQSGARVVLARTGVVLSPAGGMLRRMRPLF  180
			  	181  SVGLGARLGSGRQYMSWISLEDEVRALQFAIAQPNLSGPVNLTGPAPVTNAEFTTAFGRA  240
			  	241  VNRPTPLMLPSVAVRAAFGEFADEGLLIGQRAIPSALERAGFQFHHNTIGEALGYATTRP  300
			  	301  G

Known structures in the PDB
No Known structures
1 31 61 91 121 151 181 211 241 271 301 Range: 6 to 223  |  Coverage: 72% Epimerase Range: 249 to 296  |  Coverage: 15% DUF1731 Range: 4 to 298  |  Coverage: 97% 1 Range: 4 to 296  |  Coverage: 97% 1
Number of amino acids : 301
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
EpimerasePF013706-223
DUF1731PF08338249-296
Mtb Structural Proteome models
Model Number1
Model nameRv2216
Template2B69    APDBCREDO
Template coverage5_305
Template Identity(%)20.3
Model coverage(%)97.7
Normalized DOPE score0.003

Structure Models from Chopin
Model Number1
Profilec.2.1.6 - 3.40.50.720
Click for model details
zscore4.94
Residue begin4
Residue end296
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2216Gene nameConfidence Score
Rv2215dlaT0.92
Rv2215dlaT0.92
Rv2215dlaT0.92
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions