SInCRe - Rv2136c

Tuberculist information

Gene name	Rv2136c
Protein function	Possible conserved transmembrane protein
Functional category(tuberculist)	cell wall and cell processes
Gene location(kb)	2396.01
Molecular mass(da)	29733
External sites	TB Database TubercuList WebTB

Protein sequence

Number of amino acids : 276

	  		  	1    MSWWQVIVLAAAQGLTEFLPVSSSGHLAIVSRIFFSGDAGASFTAVSQLGTEAAVVIYFA   60
			  	61   RDIVRILSAWLHGLVVKAHRNTDYRLGWYVIIGTIPICILGLFFKDDIRSGVRNLWVVVT  120
			  	121  ALVVFSGVIALAEYVGRQSRHIERLTWRDAVVVGIAQTLALVPGVSRSGSTISAGLFLGL  180
			  	181  DRELAARFGFLLAIPAVFASGLFSLPDAFHPVTEGMSATGPQLLVATLIAFVLGLTAVAW  240
			  	241  LLRFLVRHNMYWFVGYRVLVGTGMLVLLATGTVAAT

Known structures in the PDB

No Known structures

Number of amino acids : 276

Domains assigned based on sequence.

Mtb Structural proteome models

CHOPIN models

Profile-based domain assignment

Structural/Functional domain family	Pfam acc.no./SCOP ID	Domain Region
BacA	PF02673	11-271

Mtb Structural Proteome models

Model Number	1
Model name	Rv2136c
Template	1T9X APDB CREDO
Template coverage	864_1030
Template Identity(%)	14.4
Model coverage(%)	75.0
Normalized DOPE score	1.14

Structure Models from Chopin

CHOPIN models not available for this query

Binding pockets

STRING

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Protein interacting with Rv2136c	Gene name	Confidence Score
Rv2748c	ftsK	0.926
Rv2748c	ftsK	0.926
Rv2748c	ftsK	0.926

Potential ligand/drug binding sites

No binding sites identified

Similarity to known drug target from sensitive sequence analysis

No drug targets

List of small molecules tested from TIBLE

Data not available

Off-target activity - ligand based from TIBLE

Data not available

Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.

Data not available

STITCH interactions

Chemical Name	Confidence score	Molecular Weight
undecaprenyl phosphatePubChem	0.95	847.282