SInCRe - Rv2032

Tuberculist information

Gene name	acg
Protein function	Conserved protein Acg
Functional category(tuberculist)	conserved hypotheticals
Gene location(kb)	2279.13
Molecular mass(da)	36559.3
External sites	TB Database TubercuList WebTB

Protein sequence

Number of amino acids : 331

	  		  	1    MPDTMVTTDVIKSAVQLACRAPSLHNSQPWRWIAEDHTVALFLDKDRVLYATDHSGREAL   60
			  	61   LGCGAVLDHFRVAMAAAGTTANVERFPNPNDPLHLASIDFSPADFVTEGHRLRADAILLR  120
			  	121  RTDRLPFAEPPDWDLVESQLRTTVTADTVRIDVIADDMRPELAAASKLTESLRLYDSSYH  180
			  	181  AELFWWTGAFETSEGIPHSSLVSAAESDRVTFGRDFPVVANTDRRPEFGHDRSKVLVLST  240
			  	241  YDNERASLLRCGEMLSAVLLDATMAGLATCTLTHITELHASRDLVAALIGQPATPQALVR  300
			  	301  VGLAPEMEEPPPATPRRPIDEVFHVRAKDHR

Known structures in the PDB

No Known structures

Number of amino acids : 331

Domains assigned based on sequence.

Mtb Structural proteome models

CHOPIN models

Profile-based domain assignment

Structural/Functional domain family	Pfam acc.no./SCOP ID	Domain Region
Nitroreductase	PF00881	149-303

Mtb Structural Proteome models

Model Number	1
Model name	Rv2032
Template	1BKJ APDB CREDO
Template coverage	2_184
Template Identity(%)	19.7
Model coverage(%)	66.5
Normalized DOPE score	1.041

Structure Models from Chopin

CHOPIN models not available for this query

Binding pockets

STRING

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Protein interacting with Rv2032	Gene name	Confidence Score
Rv2029c	pfkB	0.928
Rv2031c	hspX	0.926

Potential ligand/drug binding sites

No binding sites identified

Similarity to known drug target from sensitive sequence analysis

No drug targets

List of small molecules tested from TIBLE

Data not available

Off-target activity - ligand based from TIBLE

Data not available

Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.

Data not available

STITCH interactions

No high confidence interactions