Rv1842c

Tuberculist information
Gene nameRv1842c
Protein functionConserved hypothetical membrane protein
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)2090.72
Molecular mass(da)48092
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 455
	  		  	1    VNLTDTVATILAILALTAGTGVFVAAEFSLTALDRSTVEANARGGTSRDRFIQRAHHRLS   60
			  	61   FQLSGAQLGISITTLATGYLTEPLVAELPHPGLVAVGMSDRVADGLITFFALVIVTSLSM  120
			  	121  VFGELVPKYLAVARPLRTARSVVAGQVLFSLLLTPAIRLTNGAANWIVRRLGIEPAEELR  180
			  	181  SARTPQELVSLVRSSARSGALDDATAWLMRRSLQFGALTAEELMTPRSKIVALQTDDTIA  240
			  	241  DLVAAAAASGFSRFPVVEGDLDATVGIVHVKQVFEVPPGDRAHTLLTTVAEPVAVVPSTL  300
			  	301  DGDAVMAQVRASALQTAMVVDEYGGTAGMVTLEDLIEEIVGDVRDEHDDATPDVVAAGNG  360
			  	361  WRVSGLLRIDEVASATGYRAPDGPYETIGGLVLRELGHIPVAGETVELTALDQDGLPDDS  420
			  	421  MRWLATVIQMDGRRIDLLELIKMGGHADPGSGRGR

Known structures in the PDB
No Known structures
1 46 91 136 181 226 271 316 361 406 451 Range: 8 to 205  |  Coverage: 43% DUF21 Range: 220 to 279  |  Coverage: 12% CBS Range: 282 to 341  |  Coverage: 12% CBS Range: 354 to 444  |  Coverage: 19% CorC_HlyC Range: 218 to 386  |  Coverage: 36% 1 Range: 354 to 444  |  Coverage: 19% 1
Number of amino acids : 455
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
DUF21PF015958-205
CBSPF00571220-279
CBSPF00571282-341
CorC_HlyCPF03471354-444
Mtb Structural Proteome models
Model Number1
Model nameRv1842c
Template1PVM    APDBCREDO
Template coverage3_177
Template Identity(%)17.8
Model coverage(%)36.9
Normalized DOPE score0.266

Structure Models from Chopin
Model Number1
Profiled.145.1.4 - 3.30.465.10
Click for model details
zscore15.29
Residue begin354
Residue end444
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1842cGene nameConfidence Score
Rv1841cRv1841c0.941
Rv1841cRv1841c0.941
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
selenomethioninePubChem0.785196.106
SeMetPubChem0.785196.106