Rv1841c

Tuberculist information
Gene nameRv1841c
Protein functionConserved hypothetical membrane protein
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)2089.68
Molecular mass(da)36685
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 345
	  		  	1    MDVLSAVLLALLLIGANAFFVGAEFALISARRDRLEALAEQGKATAVTVIRAGEQLPAML   60
			  	61   TGAQLGVTVSSILLGRVGEPAVVKLLQLSFGLSGVPPALLHTLSLAIVVALHVLLGEMVP  120
			  	121  KNIALAGPERTAMLLVPPYLVYVRLARPFIAFYNNCANAILRLVGVQPKDELDIAVSTAE  180
			  	181  LSEMIAESLSEGLLDHEEHTRLTRALRIRTRLVADVAVPLVNIRAVQVSAVGSGPTIGGV  240
			  	241  EQALAQTGYSRFPVVDRGGRFIGYLHIKDVLTLGDNPQTVIDLAVVRPLPRVPQSLPLAD  300
			  	301  ALSRMRRINSHLALVTADNGSVVGMVALEDVVEDLVGTMRDGTHR

Known structures in the PDB
No Known structures
1 35 69 103 137 171 205 239 273 307 341 Range: 5 to 198  |  Coverage: 55% DUF21 Range: 236 to 276  |  Coverage: 11% CBS Range: 280 to 337  |  Coverage: 16% CBS Range: 219 to 335  |  Coverage: 33% 1
Number of amino acids : 345
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
DUF21PF015955-198
CBSPF00571236-276
CBSPF00571280-337
Mtb Structural Proteome models
Model Number1
Model nameRv1841c
Template1PVM    APDBCREDO
Template coverage4_125
Template Identity(%)20.5
Model coverage(%)33.6
Normalized DOPE score-0.593

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1841cGene nameConfidence Score
Rv1842cRv1842c0.941
Rv1842cRv1842c0.941
Rv1842cRv1842c0.941
Rv1836cRv1836c0.913
Rv1836cRv1836c0.913
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
selenomethioninePubChem0.707196.106
SeMetPubChem0.707196.106