Rv1827

Tuberculist information
Gene namegarA
Protein functionConserved protein with FHA domain, GarA
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)2072.6
Molecular mass(da)17218.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 162
	  		  	1    VTDMNPDIEKDQTSDEVTVETTSVFRADFLSELDAPAQAGTESAVSGVEGLPPGSALLVV   60
			  	61   KRGPNAGSRFLLDQAITSAGRHPDSDIFLDDVTVSRRHAEFRLENNEFNVVDVGSLNGTY  120
			  	121  VNREPVDSAVLANGDEVQIGKFRLVFLTGPKQGEDDGSTGGP

Known structures in the PDB
PDB ID2KFU
Total residue count162
Number of chains1
MethodNMR
ResolutionN/A
1 17 33 49 65 81 97 113 129 145 161 Range: 77 to 140  |  Coverage: 38% FHA Range: 5 to 153  |  Coverage: 91% 1 Range: 11 to 162  |  Coverage: 93% 1
Number of amino acids : 162
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
FHAPF0049877-140
Mtb Structural Proteome models
Model Number1
Model nameRv1827
Template2FF4    APDBCREDO
Template coverage238_385
Template Identity(%)25.7
Model coverage(%)91.4
Normalized DOPE score-0.209

Structure Models from Chopin
Model Number1
Profileb.26.1.2 - 2.60.200.20
Click for model details
zscore10.41
Residue begin11
Residue end162
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1827Gene nameConfidence Score
Rv0014cpknB0.972
Rv0014cpknB0.972
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions