Rv1760

Tuberculist information
Gene nameRv1760
Protein functionPossible triacylglycerol synthase (diacylglycerol acyltransferase)
Functional category(tuberculist)lipid metabolism
Gene location(kb)1993.15
Molecular mass(da)54092.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 502
	  		  	1    MPRGCAGARFACNACLNFLAGLGISEPISPGWAAMERLSGLDAFFLYMETPSQPLNVCCV   60
			  	61   LELDTSTMPGGYTYGRFHAALEKYVKAAPEFRMKLADTELNLDHPVWVDDDNFQIRHHLR  120
			  	121  RVAMPAPGGRRELAEICGYIAGLPLDRDRPLWEMWVIEGGARSDTVAVMLKVHHAVVDGV  180
			  	181  AGANLLSHLCSLQPDAPAPQPVRGTGGGNVLQIAASGLEGFASRPVRLATVVPATVLTLV  240
			  	241  RTLLRAREGRTMAAPFSAPPTPFNGPLGRLRNIAYTQLDMRDVKRVKDRFGVTINDVVVA  300
			  	301  LCAGALRRFLLEHGVLPEAPLVATVPVSVHDKSDRPGRNQATWMFCRVPSQISDPAQRIR  360
			  	361  TIAAGNTVAKDHAAAIGPTLLHDWIQFGGSTMFGAAMRILPHISITHSPAYNLILSNVPG  420
			  	421  PQAQLYFLGCRMDSMFPLGPLLGNAGLNITVMSLNGELGVGIVSCPDLLPDLWGVADGFP  480
			  	481  EALKELLECSDDQPEGSNHQDS

Known structures in the PDB
No Known structures
1 51 101 151 201 251 301 351 401 451 501 Range: 38 to 298  |  Coverage: 51% WES_acyltransf Range: 38 to 500  |  Coverage: 92% 1 Range: 30 to 228  |  Coverage: 39% 1
Number of amino acids : 502
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
WES_acyltransfPF0300738-298
Mtb Structural Proteome models
Model Number1
Model nameRv1760
Template1L5A    APDBCREDO
Template coverage1_417
Template Identity(%)13.9
Model coverage(%)92.0
Normalized DOPE score0.513

Structure Models from Chopin
Model Number1
Profilec.43.1.2
Click for model details
zscore4.87
Residue begin30
Residue end228
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1760Gene nameConfidence Score
Rv1543Rv15430.957
Rv3391acrA10.954
Rv3391acrA10.954
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions