Rv1758

Tuberculist information
Gene namecut1
Protein functionProbable cutinase Cut1
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)1989.04
Molecular mass(da)17868.3
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 174
	  		  	1    MPGRFREDFIDALRSKIGEKSMGVYGVDYPATTDFPTAMAGIYDAGTHVEQTAANCPQSK   60
			  	61   LVLGGFSQGAAVMGFVTAAAIPDGAPLDAPRPMPPEVADHVAAVTLFGMPSVAFMHSIGA  120
			  	121  PPIVIGPLYAEKTIQLCAPGDPVCSSGGNWAAHNGYADDGMVEQAAVFAAGRLG

Known structures in the PDB
No Known structures
1 18 35 52 69 86 103 120 137 154 171 Range: 1 to 174  |  Coverage: 99% Cutinase Range: 9 to 174  |  Coverage: 94% 1 Range: 1 to 174  |  Coverage: 99% 1
Number of amino acids : 174
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
CutinasePF010831-174
Mtb Structural Proteome models
Model Number1
Model nameRv1758
Template1G66    APDBCREDO
Template coverage25_207
Template Identity(%)24.7
Model coverage(%)94.8
Normalized DOPE score-0.255

Structure Models from Chopin
Model Number1
Profilec.69.1.30 - 3.40.50.1820
Click for model details
zscore25.88
Residue begin1
Residue end174
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1758Gene nameConfidence Score
Rv1777cyp1440.912
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions