Rv1722

Tuberculist information
Gene nameRv1722
Protein functionPossible carboxylase
Functional category(tuberculist)lipid metabolism
Gene location(kb)1947.86
Molecular mass(da)55428.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 494
	  		  	1    VIVPAREPEPQPRRVLNGLSDVRAFFHNNTVPLYFISPTPFNLLGIYRWIRNFFYLTYYD   60
			  	61   SFEGEHSRVFVPRRRDRRDFDGMGDVCNHLLRDPETLEFIKNRGPGGKACFVMLDEETQA  120
			  	121  LARQAGLEVMHPPAELRHRLESKIVMTRLADEAGVPSVPHVIGRVSSYDELSALAHGAGL  180
			  	181  GDDLVVEAAYGNAGSATFFVRGLRDWDQCAGGIVGQPEIKVMKRIRNVEVCIEATVTRHG  240
			  	241  TVIGPAMTSLVGYPELTPYRGAWCGNDVWRGALPPAQTRAAREMVAKLGDVLSREGYRGY  300
			  	301  FEVDLLHDLDADELYLGEVNPRLSGASPMTNLTTEAYADMPLFLFHLLEYMDVDYELDIE  360
			  	361  AINSRWERGYGEDEVWGQLIMSETSPDLELFTATPRTGMWRLNHDGRVSFARQGNDWATM  420
			  	421  LDESEAFYMRVAAPGDLRCEGAQLGVLVTRGHLQTDDYQLTERGRRWIDGLKAQFASTPL  480
			  	481  TPAAPIVSRLVARA

Known structures in the PDB
No Known structures
1 50 99 148 197 246 295 344 393 442 491 Range: 139 to 328  |  Coverage: 38% ATP-grasp_4 Range: 6 to 474  |  Coverage: 94% 1 Range: 142 to 372  |  Coverage: 46% 1
Number of amino acids : 494
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
ATP-grasp_4PF13535139-328
Mtb Structural Proteome models
Model Number1
Model nameRv1722
Template1A9X    APDBCREDO
Template coverage3_469
Template Identity(%)11.6
Model coverage(%)94.7
Normalized DOPE score0.439

Structure Models from Chopin
Model Number1
Profiled.142.1.1
Click for model details
zscore15.65
Residue begin142
Residue end372
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1722Gene nameConfidence Score
Rv2531cRv2531c0.934
Rv2531cRv2531c0.934
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
hexadecanePubChem0.732226.441