SInCRe - Rv1718

Tuberculist information

Gene name	Rv1718
Protein function	Conserved hypothetical protein
Functional category(tuberculist)	conserved hypotheticals
Gene location(kb)	1944.81
Molecular mass(da)	29243.8
External sites	TB Database TubercuList WebTB

Protein sequence

Number of amino acids : 272

	  		  	1    MSIVITVAPTGPIATKADNPALPTSPEEIATAVEQAYHAGAAVAHIHLRDENERPTADPN   60
			  	61   IARRAMDLIGERCPILIQLSTGVGLTVPFEQREQLVELRPRMATLNPCSMSFGAGEFRNP  120
			  	121  PQAVRRLAARMRELDIKPELEIYDTGHLEACLRLWAEDLLAEPLQFSIVLGVRGGMAATA  180
			  	181  DNLLTMVRRLPPGAIWQVIAIGKANMELTAMGLALGGNARVGLEDTLYLRKGELAPSNLA  240
			  	241  LVSRTIRLAEALDLPIASVEEAEAALQLPGTS

Known structures in the PDB

No Known structures

Number of amino acids : 272

Domains assigned based on sequence.

Mtb Structural proteome models

CHOPIN models

Profile-based domain assignment

Structural/Functional domain family	Pfam acc.no./SCOP ID	Domain Region
DUF849	PF05853	2-268

Mtb Structural Proteome models

Structure models not available for this query

Structure Models from Chopin

Model Number	1
Profile	c.1.2.2 - 3.20.20.70 Click for model details
zscore	4.96
Residue begin	5
Residue end	272

Binding pockets

Structure models not available for this query

STRING

Cytoscape Web will replace the contents of this div with protein-protein interaction network.

Protein interacting with Rv1718	Gene name	Confidence Score
Rv1717	Rv1717	0.926
Rv1715	fadB3	0.906
Rv1715	fadB3	0.906

Potential ligand/drug binding sites

No binding sites identified

Similarity to known drug target from sensitive sequence analysis

No drug targets

List of small molecules tested from TIBLE

Data not available

Off-target activity - ligand based from TIBLE

Data not available

Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.

Data not available

STITCH interactions

Chemical Name	Confidence score	Molecular Weight
selenomethioninePubChem	0.772	196.106
SeMetPubChem	0.772	196.106
zincPubChem	0.756	65.409
hydride acetatePubChem	0.724	61.0599
acetatePubChem	0.724	59.044