Rv1692

Tuberculist information
Gene nameRv1692
Protein functionProbable phosphatase
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)1916.7
Molecular mass(da)37010.9
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 353
	  		  	1    MKSIAQEHDCLLIDLDGTVFCGRQPTGGAVQSLSQVRSRKLFVTNNASRSADEVAAHLCE   60
			  	61   LGFTATGEDVVTSAQSAAHLLAGQLAPGARVLIVGTEALANEVAAVGLRPVRRFEDRPDA  120
			  	121  VVQGLSMTTGWSDLAEAALAIRAGALWVAANVDPTLPTERGLLPGNGSMVAALRTATGMD  180
			  	181  PRVAGKPAPALMTEAVARGDFRAALVVGDRLDTDIEGANAAGLPSLMVLTGVNSAWDAVY  240
			  	241  AEPVRRPTYIGHDLRSLHQDSKLLAVAPQPGWQIDVGGGAVTVCANGDVDDLEFIDDGLS  300
			  	301  IVRAVASAVWEARAADLHQRPLRIEAGDERARAALQRWSLMRSDHPVTSVGTQ

Known structures in the PDB
PDB ID4I9F
Total residue count722
Number of chains2
MethodX-RAY
Resolution2.21
PDB ID4I9G
Total residue count722
Number of chains2
MethodX-RAY
Resolution3.25
1 36 71 106 141 176 211 246 281 316 351 Range: 11 to 109  |  Coverage: 27% Hydrolase_6 Range: 183 to 257  |  Coverage: 20% Hydrolase_like Range: 7 to 256  |  Coverage: 70% 1 Range: 2 to 265  |  Coverage: 74% 1 Range: 97 to 182  |  Coverage: 24% 2
Number of amino acids : 353
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Hydrolase_6PF1334411-109
Hydrolase_likePF13242183-257
Mtb Structural Proteome models
Model Number1
Model nameRv1692
Template1YV9    APDBCREDO
Template coverage4_253
Template Identity(%)31.6
Model coverage(%)70.5
Normalized DOPE score-0.347

Structure Models from Chopin
Model Number1
Profilec.108.1.14
Click for model details
zscore43.62
Residue begin2
Residue end265
Model Number2
Profile3.40.50.10410
Click for model details
zscore12.22
Residue begin97
Residue end182
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1692Gene nameConfidence Score
Rv1691Rv16910.991
Rv1693Rv16930.984
Rv1695ppnK0.978
Rv1694tlyA0.927
Rv1694tlyA0.927
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
magnesiumPubChem0.7424.305