SInCRe - Rv1691

Tuberculist information

Gene name	Rv1691
Protein function	Conserved hypothetical protein
Functional category(tuberculist)	conserved hypotheticals
Gene location(kb)	1915.95
Molecular mass(da)	26650
External sites	TB Database TubercuList WebTB

Protein sequence

Number of amino acids : 250

	  		  	1    VVDDRQGRRGGRRPRSAAADNRPAFRDGPAIPPGIHARQLAPEIRRELSTLDRATADAVA   60
			  	61   CHLVAAGELIDDDPEAALRHARAARVRASRIAAVREAVGIAAYRCGDWAQALAELRAARR  120
			  	121  MGSKSPLLALIADCERGLGRPQRAIELARGSEAVELSGDAADELRIVAAGARADLGQLEQ  180
			  	181  ALTVLSTPQLDPGRTGSTAARLFYAYAEILLALGRGDEALQWFLRSAAADIDGVTDAEDR  240
			  	241  VDELGAREQK

Known structures in the PDB

No Known structures

Number of amino acids : 250

Domains assigned based on sequence.

Mtb Structural proteome models

CHOPIN models

Profile-based domain assignment

Structural/Functional domain family	Pfam acc.no./SCOP ID	Domain Region
TPR_5	PF12688	131-235

Mtb Structural Proteome models

Model Number	1
Model name	Rv1691
Template	1XNF APDB CREDO
Template coverage	47_283
Template Identity(%)	12.7
Model coverage(%)	98.8
Normalized DOPE score	0.181

Structure Models from Chopin

Model Number	1
Profile	a.118.8.2 - 1.25.40.10 Click for model details
zscore	5.46
Residue begin	3
Residue end	250

Binding pockets

STRING

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Protein interacting with Rv1691	Gene name	Confidence Score
Rv1692	Rv1692	0.991
Rv1692	Rv1692	0.991
Rv1693	Rv1693	0.977
Rv1695	ppnK	0.971

Potential ligand/drug binding sites

No binding sites identified

Similarity to known drug target from sensitive sequence analysis

No drug targets

List of small molecules tested from TIBLE

Data not available

Off-target activity - ligand based from TIBLE

Data not available

Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.

Data not available

STITCH interactions

No high confidence interactions