Rv1680

Tuberculist information
Gene nameRv1680
Protein functionHypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)1904.43
Molecular mass(da)30214
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 274
	  		  	1    MSTEPLVVGAVAYTPNVVPIWEGIRGYFQDSESPDTQMDFVLYSNYARLVDSLIAGHIDI   60
			  	61   AWNTNLAYVRTVLQTGGRCTPLAQRDTDVDYTTVFVAHAGSDLHGAKDIAGKRLALGSAD  120
			  	121  SAHAAILPLYYLRRAGIAESDLQVIRFDTDIGKHGDTGRSELDAVDAVLAGEADVAAIGS  180
			  	181  STWAAMGAAELMGESLTEVWRTDGYCHCMFTALDTLPAERYQPWLDRLLAMSWDDSEHRK  240
			  	241  ILELEGLRRWVPPHLDGYKPLFEAVQEQGIDPRW

Known structures in the PDB
No Known structures
1 28 55 82 109 136 163 190 217 244 271 Range: 14 to 258  |  Coverage: 89% Phosphonate-bd Range: 2 to 270  |  Coverage: 97% 1 Range: 1 to 274  |  Coverage: 99% 1
Number of amino acids : 274
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Phosphonate-bdPF1297414-258
Mtb Structural Proteome models
Model Number1
Model nameRv1680
Template1US5    APDBCREDO
Template coverage17_312
Template Identity(%)14.9
Model coverage(%)97.8
Normalized DOPE score0.011

Structure Models from Chopin
Model Number1
Profilec.94.1.2 - 3.40.190.10
Click for model details
zscore13.6
Residue begin1
Residue end274
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1680Gene nameConfidence Score
Rv1679fadE160.982
Rv1679fadE160.982
Rv1679fadE160.982
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions