Rv1634

Tuberculist information
Gene nameRv1634
Protein functionPossible drug efflux membrane protein
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)1839.17
Molecular mass(da)47681.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 471
	  		  	1    VTETASETGSWRELLSRYLGTSIVLAGGVALYATNEFLTISLLPSTIADIGGSRLYAWVT   60
			  	61   TLYLVGSVVAATTVNTMLLRVGARSSYLMGLAVFGLASLVCAAAPSMQILVAGRTLQGIA  120
			  	121  GGLLAGLGYALINSTLPKSLWTRGSALVSAMWGVATLIGPATGGLFAQLGLWRWAFGVMT  180
			  	181  LLTALMAMLVPVALGAGGVGPGGETPVGSTHKVPVWSLLLMGAAALAISVAALPNYLVQT  240
			  	241  AGLLAAAALLVAVFVVVDWRIHAAVLPPSVFGSGPLKWIYLTMSVQMIAAMVDTYVPLFG  300
			  	301  QRLGHLTPVAAGFLGAALAVGWTVGEVASASLNSARVIGHVVAAAPLVMASGLALGAVTQ  360
			  	361  RADAPVGIIALWALALLIIGTGIGIAWPHLTVRAMDSVADPAESSAAAAAINVVQLISGA  420
			  	421  FGAGLAGVVVNTAKGGEVAAARGLYMAFTVLAAAGVIASYQATHRDRRLPR

Known structures in the PDB
No Known structures
1 48 95 142 189 236 283 330 377 424 471 Range: 25 to 423  |  Coverage: 84% MFS_1 Range: 52 to 447  |  Coverage: 83% 1 Range: to   |  Coverage: 0% 1 Range: to   |  Coverage: 0% 2
Number of amino acids : 471
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
MFS_1PF0769025-423
Mtb Structural Proteome models
Model Number1
Model nameRv1634
Template2B2H    APDBCREDO
Template coverage2_372
Template Identity(%)19.7
Model coverage(%)83.9
Normalized DOPE score0.591

Structure Models from Chopin
Model Number1
Profilef.38.1.1
Click for model details
zscore12.84
Residue begin
Residue end
Model Number2
Profilef.38.1.2
Click for model details
zscore4.56
Residue begin
Residue end
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1634Gene nameConfidence Score
Rv1633uvrB0.915
Rv1633uvrB0.915
Rv1633uvrB0.915
Rv1633uvrB0.915
Rv1632cRv1632c0.909
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions