Rv1593c

Tuberculist information
Gene nameRv1593c
Protein functionConserved protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)1794
Molecular mass(da)25907.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 236
	  		  	1    MAHGSTAHEVLAVVFQVRGVGMSRGAAKPQLNVLLWQRAKEPQRGAWSLPGGRLRNDEDM   60
			  	61   TSSVRRQLAEKVDLRELAHLEQLAVFSDPHRLPGIRMIASTYLGVVPSPATPELPADTRW  120
			  	121  HPVSSLPPMAFDHGPMVTHARTRLIAKMSYTNIGFALAPKEFALSTLRDIYGAALGYQVD  180
			  	181  ATNLQRVLARRRVITQTGTIAQSGRSGGRPAALYRFTDSQLRVTDEFAALRPPGQL

Known structures in the PDB
No Known structures
1 24 47 70 93 116 139 162 185 208 231 Range: 8 to 141  |  Coverage: 56% NUDIX Range: 8 to 227  |  Coverage: 92% 1 Range: 1 to 236  |  Coverage: 99% 1 Range: 1 to 149  |  Coverage: 62% 2 Range: 152 to 228  |  Coverage: 32% 3
Number of amino acids : 236
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
NUDIXPF002938-141
Mtb Structural Proteome models
Model Number1
Model nameRv1593c
Template2FB1    APDBCREDO
Template coverage4_223
Template Identity(%)31.4
Model coverage(%)92.8
Normalized DOPE score0.1

Structure Models from Chopin
Model Number1
Profilea.4.5.68, d.113.1.6 - 1.10.10.10, 3.90.79.10
Click for model details
zscore35.77
Residue begin1
Residue end236
Model Number2
Profiled.113.1.6
Click for model details
zscore25.1
Residue begin1
Residue end149
Model Number3
Profilea.4.5.68
Click for model details
zscore19.36
Residue begin152
Residue end228
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1593cGene nameConfidence Score
Rv1594nadA0.961
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions