Rv1544

Tuberculist information
Gene nameRv1544
Protein functionPossible ketoacyl reductase
Functional category(tuberculist)lipid metabolism
Gene location(kb)1746.09
Molecular mass(da)28199.6
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 267
	  		  	1    MSLPKPNNQTTVVITGASSGIGVELARGLAGRGFPLMLVARRRERLDELADQLRQEHCVG   60
			  	61   VEVLPLDLADTQARAQLADRLRSDAIAGLCNSAGFGTSGRFWELPFARESEEVVLNALAL  120
			  	121  MELTHAALPGMVKRGAGAVLNIASIAGFQPIPYMAVYSATKAFVLTFSEAVQEELHGTGV  180
			  	181  SVTALCPGPVPTEWAEIASAERFSIPLAQVSPHDVAEAAIAGMLSGKRTVVPGIVPKFVS  240
			  	241  TSGRFAPRSLLLPAIRIGNRLRGGPSR

Known structures in the PDB
No Known structures
1 27 53 79 105 131 157 183 209 235 261 Range: 10 to 176  |  Coverage: 62% adh_short Range: 4 to 266  |  Coverage: 98% 1 Range: 1 to 267  |  Coverage: 99% 1
Number of amino acids : 267
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
adh_shortPF0010610-176
Mtb Structural Proteome models
Model Number1
Model nameRv1544
Template1XSE    APDBCREDO
Template coverage29_294
Template Identity(%)22.4
Model coverage(%)98.1
Normalized DOPE score-0.152

Structure Models from Chopin
Model Number1
Profilec.2.1.2 - 3.40.50.720
Click for model details
zscore14.72
Residue begin1
Residue end267
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1544Gene nameConfidence Score
Rv1543Rv15430.912
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions