Rv1526c

Tuberculist information
Gene nameRv1526c
Protein functionProbable glycosyltransferase
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)1720.78
Molecular mass(da)45696.3
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 426
	  		  	1    MKFVLAVHGTRGDVEPCAAVGVELRRRGHAVHMAVPPNLIEFVESAGLTGVAYGPDSDEQ   60
			  	61   INTVAAFVRNLTRAQNPLNLARAVKELFVEGWAEMGTTLTTLADGADLVMTGQTYHGVAA  120
			  	121  NVAEYYDIPAAALHHFPMQVNGQIAIPSIPTPATLVRATMKVSWRLYAYVSKDADRAQRR  180
			  	181  ELGLPPAPAPAVRRLAERGAPEIQAYDPVFFPGLAAEWSDRRPFVGPLTMELHSEPNEEL  240
			  	241  ESWIAAGTPPIYFGFGSTPVQTPVQTLAMISDVCAQLGERALIYSPAANSTRIRHADHVK  300
			  	301  RVGLVNYSTILPKCRAVVHHGGAGTTAAGLRAGMPTLILWDVADQPIWAGAVQRLKVGSA  360
			  	361  KRFTNITRGSLLKELRSILAPECAARAREISTRMTRPTAAVTAAADLLEATARQTPGSTP  420
			  	421  SSSPGR

Known structures in the PDB
No Known structures
1 43 85 127 169 211 253 295 337 379 421 Range: 3 to 145  |  Coverage: 33% Glyco_transf_28 Range: 247 to 389  |  Coverage: 33% Glycos_transf_1 Range: 1 to 414  |  Coverage: 96% 1 Range: 1 to 422  |  Coverage: 98% 1
Number of amino acids : 426
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Glyco_transf_28PF030333-145
Glycos_transf_1PF00534247-389
Mtb Structural Proteome models
Model Number1
Model nameRv1526c
Template1RRV    APDBCREDO
Template coverage1_401
Template Identity(%)26.7
Model coverage(%)96.9
Normalized DOPE score-0.043

Structure Models from Chopin
Model Number1
Profilec.87.1.5
Click for model details
zscore62.21
Residue begin1
Residue end422
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1526cGene nameConfidence Score
Rv1511gmdA0.937
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
DrugBank IDDrug Name
DB00512DrugBankVancomycin
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
GDP-mannosePubChem0.9605.341