Rv1212c

Tuberculist information
Gene nameglgA
Protein functionPutative glycosyl transferase GlgA
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)1354.5
Molecular mass(da)41532.5
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 387
	  		  	1    MRVAMLTREYPPEVYGGAGVHVTELVAYLRRLCAVDVHCMGAPRPGAFAYRPDPRLGSAN   60
			  	61   AALSTLSADLVMANAASAATVVHSHTWYTALAGHLAAILYDIPHVLTAHSLEPLRPWKKE  120
			  	121  QLGGGYQVSTWVEQTAVLAANAVIAVSSAMRNDMLRVYPSLDPNLVHVIRNGIDTETWYP  180
			  	181  AGPARTGSVLAELGVDPNRPMAVFVGRITRQKGVVHLVTAAHRFRSDVQLVLCAGAADTP  240
			  	241  EVADEVRVAVAELARNRTGVFWIQDRLTIGQLREILSAATVFVCPSVYEPLGIVNLEAMA  300
			  	301  CATAVVASDVGGIPEVVADGITGSLVHYDADDATGYQARLAEAVNALVADPATAERYGHA  360
			  	361  GRQRCIQEFSWAYIAEQTLDIYRKVCA

Known structures in the PDB
No Known structures
1 39 77 115 153 191 229 267 305 343 381 Range: 16 to 172  |  Coverage: 40% Glyco_trans_4_4 Range: 190 to 364  |  Coverage: 44% Glycos_transf_1 Range: 1 to 382  |  Coverage: 98% 1 Range: 1 to 387  |  Coverage: 99% 1
Number of amino acids : 387
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Glyco_trans_4_4PF1357916-172
Glycos_transf_1PF00534190-364
Mtb Structural Proteome models
Model Number1
Model nameRv1212c
Template2BIS    APDBCREDO
Template coverage1_425
Template Identity(%)25.7
Model coverage(%)98.4
Normalized DOPE score-0.038

Structure Models from Chopin
Model Number1
Profilec.87.1.8
Click for model details
zscore33.68
Residue begin1
Residue end387
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1212cGene nameConfidence Score
Rv1213glgC0.926
Rv1213glgC0.926
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions