Rv1178

Tuberculist information
Gene nameRv1178
Protein functionProbable aminotransferase
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)1309.36
Molecular mass(da)37702.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 362
	  		  	1    VSASLPVFPWDTLADAKALAGAHPDGIVDLSVGTPVDPVAPLIQEALAAASAAPGYPATA   60
			  	61   GTARLRESVVAALARRYGITRLTEAAVLPVIGTKELIAWLPTLLGLGGADLVVVPELAYP  120
			  	121  TYDVGARLAGTRVLRADALTQLGPQSPALLYLNSPSNPTGRVLGVDHLRKVVEWARGRGV  180
			  	181  LVVSDECYLGLGWDAEPVSVLHPSVCDGDHTGLLAVHSLSKSSSLAGYRAGFVVGDLEIV  240
			  	241  AELLAVRKHAGMMVPAPVQAAMVAALDDDAHERQQRERYAQRRAALLPALGSAGFAVDYS  300
			  	301  DAGLYLWATRGEPCRDSAAWLAQRGILVAPGDFYGPGGAQHVRVALTATDERVAAAVGRL  360
			  	361  TC

Known structures in the PDB
No Known structures
1 37 73 109 145 181 217 253 289 325 361 Range: 25 to 360  |  Coverage: 92% Aminotran_1_2 Range: 1 to 360  |  Coverage: 99% 1 Range: 1 to 362  |  Coverage: 99% 1
Number of amino acids : 362
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Aminotran_1_2PF0015525-360
Mtb Structural Proteome models
Model Number1
Model nameRv1178
Template1J32    APDBCREDO
Template coverage7_380
Template Identity(%)24.4
Model coverage(%)99.2
Normalized DOPE score-0.227

Structure Models from Chopin
Model Number1
Profilec.67.1.1
Click for model details
zscore29.62
Residue begin1
Residue end362
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1178Gene nameConfidence Score
Rv2726cdapF0.935
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
selenomethioninePubChem0.728196.106
SeMetPubChem0.728196.106