Rv1129c

Tuberculist information
Gene nameRv1129c
Protein functionProbable transcriptional regulator protein
Functional category(tuberculist)regulatory proteins
Gene location(kb)1253.07
Molecular mass(da)54087.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 486
	  		  	1    MTRSNVLPVARTYSRTFSGARLRRLRQERGLTQVALAKALDLSTSYVNQLENDQRPITVP   60
			  	61   VLLLLTERFDLSAQYFSSDSDARLVADLSDVFTDIGVEHAVSGAQIEEFVARMPEVGHSL  120
			  	121  VAVHRRLRAATEELEGYRSRATAETELPPARPMPFEEVRDFFYDRNNYIHDLDMAAERMF  180
			  	181  TESGMRTGGLDIQLAELMRDRFGISVVIDDNLPDTAKRRYHPDTKVLRVAHWLMPGQRAF  240
			  	241  QIATQLALVGQSDLISSIVATDDQLSTEARGVARIGLANYFAGAFLLPYREFHRAAEQLR  300
			  	301  YDIDLLGRRFGVGFETVCHRLSTLQRPRQRGIPFIFVRTDKAGNISKRQSATAFHFSRVG  360
			  	361  GSCPLWVVHDAFAQPERIVRQVAQMPDGRSYFWVAKTTAADGLGYLGPHKNFAVGLGCDL  420
			  	421  AHAHKLVYSTGVVLDDPSTEVPIGAGCKICNRTSCAQRAFPYLGGRVAVDENAGSSLPYS  480
			  	481  STEQSV

Known structures in the PDB
No Known structures
1 49 97 145 193 241 289 337 385 433 481 Range: 22 to 76  |  Coverage: 11% HTH_3 Range: 199 to 322  |  Coverage: 25% DUF955 Range: 323 to 479  |  Coverage: 32% DUF2083 Range: 18 to 77  |  Coverage: 12% 1 Range: 22 to 76  |  Coverage: 11% 1 Range: 11 to 88  |  Coverage: 15% 2 Range: 1 to 105  |  Coverage: 21% 3
Number of amino acids : 486
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
HTH_3PF0138122-76
DUF955PF06114199-322
DUF2083PF09856323-479
Mtb Structural Proteome models
Model Number1
Model nameRv1129c
Template1Y7Y    APDBCREDO
Template coverage14_73
Template Identity(%)35.0
Model coverage(%)12.1
Normalized DOPE score-2.298

Structure Models from Chopin
Model Number1
Profilea.35.1.3 - 1.10.260.40
Click for model details
zscore13.99
Residue begin22
Residue end76
Model Number2
Profilea.35.1.8
Click for model details
zscore10.41
Residue begin11
Residue end88
Model Number3
Profile1.10.260.40
Click for model details
zscore9.45
Residue begin1
Residue end105
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1129cGene nameConfidence Score
Rv1130prpD0.965
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions