Rv1009

Tuberculist information
Gene namerpfB
Protein functionProbable resuscitation-promoting factor RpfB
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)1128.09
Molecular mass(da)38078.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 362
	  		  	1    MLRLVVGALLLVLAFAGGYAVAACKTVTLTVDGTAMRVTTMKSRVIDIVEENGFSVDDRD   60
			  	61   DLYPAAGVQVHDADTIVLRRSRPLQISLDGHDAKQVWTTASTVDEALAQLAMTDTAPAAA  120
			  	121  SRASRVPLSGMALPVVSAKTVQLNDGGLVRTVHLPAPNVAGLLSAAGVPLLQSDHVVPAA  180
			  	181  TAPIVEGMQIQVTRNRIKKVTERLPLPPNARRVEDPEMNMSREVVEDPGVPGTQDVTFAV  240
			  	241  AEVNGVETGRLPVANVVVTPAHEAVVRVGTKPGTEVPPVIDGSIWDAIAGCEAGGNWAIN  300
			  	301  TGNGYYGGVQFDQGTWEANGGLRYAPRADLATREEQIAVAEVTRLRQGWGAWPVCAARAG  360
			  	361  AR

Known structures in the PDB
No Known structures
1 37 73 109 145 181 217 253 289 325 361 Range: 26 to 76  |  Coverage: 13% DUF348 Range: 83 to 124  |  Coverage: 11% DUF348 Range: 140 to 182  |  Coverage: 11% DUF348 Range: 194 to 272  |  Coverage: 21% G5 Range: 279 to 355  |  Coverage: 20% Transglycosylas Range: 192 to 362  |  Coverage: 46% 1 Range: 255 to 362  |  Coverage: 29% 2
Number of amino acids : 362
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
DUF348PF0399026-76
DUF348PF0399083-124
DUF348PF03990140-182
G5PF07501194-272
TransglycosylasPF06737279-355
Mtb Structural Proteome models
Model Number1
Model nameRv1009_3eo5_A
Template3EO5    APDBCREDO
Template coverage192_362
Template Identity(%)100.0
Model coverage(%)47.0
Normalized DOPE score-0.475

Model Number2
Model nameRv1009
Template1XSF    APDBCREDO
Template coverage1_108
Template Identity(%)100.0
Model coverage(%)29.6
Normalized DOPE score-0.353

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
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Protein interacting with Rv1009Gene nameConfidence Score
Rv1010ksgA0.962
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions