Rv0958

Tuberculist information
Gene nameRv0958
Protein functionPossible magnesium chelatase
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)1069.88
Molecular mass(da)49581.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 459
	  		  	1    MSPSNLPRTVGELRAAGHRERGVKQEIRENLLTALADGDNVWPGILGFDDTVIPQVERAL   60
			  	61   IAGHDFVLLGERGQGKTRLLRALAGLLDEWTPVIAGAELGEHPYTPITPESIRRAAQLGD  120
			  	121  DLPVAWKHRSERYTEKLATPDTSVADLVGDVDPIKVAEGRSLGDPETIAYGLIPRAHRGI  180
			  	181  VAVNELPDLAERIQVSMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPI  240
			  	241  KDRFGAEIRTHYPLELEAEMGVIVQEAHLSAQVSDYLMQVLARFARYLRESRSIDQRSGV  300
			  	301  SARFAIAAAETVAAAARHRGAVLGETDPVARVVDLGTVIDVLRGKLEFESGEEGREQAVL  360
			  	361  EHLLRRATADTASRVLGGIDVGSLVTAVEGGSAVTTGERVSAKDVLAAVPGLPVVDRIAR  420
			  	421  KLGAESEGERAAALELALEALYLAKRVDKVCGEGQTVYG

Known structures in the PDB
No Known structures
1 46 91 136 181 226 271 316 361 406 451 Range: 66 to 293  |  Coverage: 49% AAA_PrkA Range: 37 to 425  |  Coverage: 84% 1 Range: 255 to 371  |  Coverage: 25% 1
Number of amino acids : 459
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
AAA_PrkAPF0829866-293
Mtb Structural Proteome models
Model Number1
Model nameRv0958
Template1IN4    APDBCREDO
Template coverage19_327
Template Identity(%)18.4
Model coverage(%)84.5
Normalized DOPE score1.086

Structure Models from Chopin
Model Number1
Profile1.10.8.300
Click for model details
zscore11.93
Residue begin255
Residue end371
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0958Gene nameConfidence Score
Rv0959Rv09590.991
Rv1485hemZ0.919
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
protoporphyrinPubChem0.9562.658