Rv0891c

Tuberculist information
Gene nameRv0891c
Protein functionPossible transcriptional regulatory protein
Functional category(tuberculist)regulatory proteins
Gene location(kb)992.598
Molecular mass(da)31199.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 285
	  		  	1    VLFNAVHNSLPPNIDIDHAILRGEDHPPTCAKCVARVRISALGSLDLRYHSLRCYAAPPD   60
			  	61   VGRCEFVPPRRRVLIANQGLDVSRLPPTGTVTLLLADVEESTHLWQMCPEDMATAIAHLD  120
			  	121  HTVSEAITNHGGVQPVKRYEGDSFVAAFTRASDAAACALDLQRTSLAPIRLRIGLHTGEV  180
			  	181  QLRDELYVGPTINRTARLRDLAHGGQVVLSAATGDLVTGRLPADAWLVDLGRHPLRGLPR  240
			  	241  PEWVMQLCHPDIREKFPPLRTAKSSPTSILPAQFTTFVGRRAQIS

Known structures in the PDB
No Known structures
1 29 57 85 113 141 169 197 225 253 281 Range: 84 to 246  |  Coverage: 56% Guanylate_cyc Range: 79 to 262  |  Coverage: 64% 1 Range: 1 to 266  |  Coverage: 92% 1
Number of amino acids : 285
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Guanylate_cycPF0021184-246
Mtb Structural Proteome models
Model Number1
Model nameRv0891c
Template1FX4    APDBCREDO
Template coverage876_1105
Template Identity(%)32.6
Model coverage(%)64.2
Normalized DOPE score-0.3

Structure Models from Chopin
Model Number1
Profiled.58.29.1 - 3.30.70.1230
Click for model details
zscore13.95
Residue begin1
Residue end266
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0891cGene nameConfidence Score
Rv0890cRv0890c0.977
Rv0890cRv0890c0.977
Rv1264Rv12640.959
Rv2212Rv22120.95
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions