Rv0849

Tuberculist information
Gene nameRv0849
Protein functionProbable conserved integral membrane transport protein
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)946.056
Molecular mass(da)44513.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 419
	  		  	1    MGARAIFRGFNRPSRVLMINQFGINIGFYMLMPYLADYLAGPLGLAAWAVGLVMGVRNFS   60
			  	61   QQGMFFVGGTLADRFGYKPLIIAGCLIRTGGFALLVVAQSLPSVLIAAAATGFAGALFNP  120
			  	121  AVRGYLAAEAGERKIEAFAMFNVFYQSGILLGPLVGLVLLALDFRITVLAAAGVFGLLTV  180
			  	181  AQLVALPQHRADSEREKTSILQDWRVVVRNRPFLTLAAAMTGCYALSFQIYLALPMQASI  240
			  	241  LMPRNQYLLIAAMFAVSGLVAVGGQLRITRWFAVRWGAERSLVVGATILAASFIPVAVIP  300
			  	301  NGQRFGVAVAVMALVLSASLLAVASAALFPFEMRAVVALSGDRLVATHYGFYSTIVGVGV  360
			  	361  LVGNLAIGSLMSAARRLNTDEIVWGGLILVGIVAVAGLRRLDTFTSGSQNMTGRWAAPR

Known structures in the PDB
No Known structures
1 42 83 124 165 206 247 288 329 370 411 Range: 17 to 317  |  Coverage: 71% MFS_1 Range: 1 to 398  |  Coverage: 94% 1
Number of amino acids : 419
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
MFS_1PF0769017-317
Mtb Structural Proteome models
Model Number1
Model nameRv0849
Template1PW4    APDBCREDO
Template coverage14_435
Template Identity(%)15.1
Model coverage(%)94.7
Normalized DOPE score0.718

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0849Gene nameConfidence Score
Rv0848cysK20.935
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions