Rv0811c

Tuberculist information
Gene nameRv0811c
Protein functionConserved protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)905.234
Molecular mass(da)39414.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 368
	  		  	1    VAAVPAPDPGPDAGAIWHYGDPLGEQRAGQADAVLVDRSHRAVLTLDGGDRQTWLHSIST   60
			  	61   QHVSDLPEGASTQNLSLDGQGRVEDHWIQTELGGTTYLDTEPWRGEPLLAYLRKMVFWSM  120
			  	121  VTPRAADMAVLSLLGPRLAEERVLDALGLDVLPAEWLAVPLAGGGIVRRMPDGLAGQIEL  180
			  	181  DVVVKRGDRADWQRRLTQAGVRPAGIWAYEAHRVAHRVPARRPRLGVDTDERTIPHEVGW  240
			  	241  IGGPGAGAVHLNKGCYRGQETVARVHNLGRPPRMLVLLHLDESVQRPSTGDAVLAGGRTV  300
			  	301  GRLGTVVEHVELGPVALALLKRGLPGDTALVTGPEAEVAAVIDVDSLPPADDVGAGRRAV  360
			  	361  ERLRGGIR

Known structures in the PDB
No Known structures
1 37 73 109 145 181 217 253 289 325 361 Range: 35 to 241  |  Coverage: 55% GCV_T Range: 254 to 346  |  Coverage: 25% GCV_T_C Range: 1 to 351  |  Coverage: 95% 1 Range: 1 to 361  |  Coverage: 97% 1 Range: 35 to 241  |  Coverage: 55% 2 Range: 39 to 130  |  Coverage: 24% 3 Range: 1 to 368  |  Coverage: 99% 4 Range: 272 to 364  |  Coverage: 25% 5
Number of amino acids : 368
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
GCV_TPF0157135-241
GCV_T_CPF08669254-346
Mtb Structural Proteome models
Model Number1
Model nameRv0811c
Template1WOS    APDBCREDO
Template coverage13_359
Template Identity(%)20.7
Model coverage(%)95.1
Normalized DOPE score-0.199

Structure Models from Chopin
Model Number1
Profileb.44.2.1, d.250.1.1 - 2.40.30.110, 3.30.1360.120
Click for model details
zscore31.69
Residue begin1
Residue end361
Model Number2
Profiled.250.1.1
Click for model details
zscore23.19
Residue begin35
Residue end241
Model Number3
Profile3.30.70.1400
Click for model details
zscore17.09
Residue begin39
Residue end130
Model Number4
Profiled.250.1.1
Click for model details
zscore13.42
Residue begin1
Residue end368
Model Number5
Profileb.44.2.1
Click for model details
zscore12.45
Residue begin272
Residue end364
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0811cGene nameConfidence Score
Rv2211cgcvT0.926
Rv2211cgcvT0.926
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions