Rv0792c

Tuberculist information
Gene nameRv0792c
Protein functionProbable transcriptional regulatory protein (probably GntR-family)
Functional category(tuberculist)regulatory proteins
Gene location(kb)885.837
Molecular mass(da)28959.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 269
	  		  	1    MTSVKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLPSERELIDRSGLSRV   60
			  	61   TVRAAVGMLQRQGWLVRRQGLGTFVADPVEQELSCGVRTITEVLLSCGVTPQVDVLSHQT  120
			  	121  GPAPQRISETLGLVEVLCIRRRIRTGDQPLALVTAYLPPGVGPAVEPLLSGSADTETTYA  180
			  	181  MWERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPLEVVVFHH  240
			  	241  RPERYQFSVTLPRTLPGSGAGIIEKRDFA

Known structures in the PDB
No Known structures
1 27 53 79 105 131 157 183 209 235 261 Range: 22 to 85  |  Coverage: 23% GntR Range: 106 to 246  |  Coverage: 52% UTRA Range: 96 to 250  |  Coverage: 57% 1 Range: 19 to 252  |  Coverage: 86% 1 Range: 87 to 258  |  Coverage: 63% 2 Range: 19 to 100  |  Coverage: 30% 3
Number of amino acids : 269
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
GntRPF0039222-85
UTRAPF07702106-246
Mtb Structural Proteome models
Model Number1
Model nameRv0792c
Template2FA1    APDBCREDO
Template coverage86_240
Template Identity(%)20.0
Model coverage(%)57.2
Normalized DOPE score-0.535

Structure Models from Chopin
Model Number1
Profile1.10.10.10, 3.40.1410.10
Click for model details
zscore39.73
Residue begin19
Residue end252
Model Number2
Profiled.190.1.2 - 3.40.1410.10
Click for model details
zscore22.68
Residue begin87
Residue end258
Model Number3
Profilea.4.5.6
Click for model details
zscore20.73
Residue begin19
Residue end100
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0792cGene nameConfidence Score
Rv3332nagA0.908
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions