Rv0655

Tuberculist information
Gene namemkl
Protein functionPossible ribonucleotide-transport ATP-binding protein ABC transporter Mkl
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)751.517
Molecular mass(da)39362.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 359
	  		  	1    VRYSDSYHTTGRWQPRASTEGFPMGVSIEVNGLTKSFGSSRIWEDVTLTIPAGEVSVLLG   60
			  	61   PSGTGKSVFLKSLIGLLRPERGSIIIDGTDIIECSAKELYEIRTLFGVLFQDGALFGSMN  120
			  	121  LYDNTAFPLREHTKKKESEIRDIVMEKLALVGLGGDEKKFPGEISGGMRKRAGLARALVL  180
			  	181  DPQIILCDEPDSGLDPVRTAYLSQLIMDINAQIDATILIVTHNINIARTVPDNMGMLFRK  240
			  	241  HLVMFGPREVLLTSDEPVVRQFLNGRRIGPIGMSEEKDEATMAEEQALLDAGHHAGGVEE  300
			  	301  IEGVPPQISATPGMPERKAVARRQARVREMLHTLPKKAQAAILDDLEGTHKYAVHEIGQ

Known structures in the PDB
No Known structures
1 36 71 106 141 176 211 246 281 316 351 Range: 43 to 192  |  Coverage: 41% ABC_tran Range: 24 to 359  |  Coverage: 93% 1 Range: 1 to 350  |  Coverage: 97% 1
Number of amino acids : 359
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
ABC_tranPF0000543-192
Mtb Structural Proteome models
Model Number1
Model nameRv0655
Template1V43    APDBCREDO
Template coverage9_366
Template Identity(%)24.4
Model coverage(%)93.3
Normalized DOPE score0.665

Structure Models from Chopin
Model Number1
Profilec.37.1.12
Click for model details
zscore30.35
Residue begin1
Residue end350
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0655Gene nameConfidence Score
Rv0168yrbE1B0.907
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions