Rv0635

Tuberculist information
Gene namehadA
Protein function(3R)-hydroxyacyl-ACP dehydratase subunit HadA
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)731.93
Molecular mass(da)17448.5
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 158
	  		  	1    VALSADIVGMHYRYPDHYEVEREKIREYAVAVQNDDAWYFEEDGAAELGYKGLLAPLTFI   60
			  	61   CVFGYKAQAAFFKHANIATAEAQIVQVDQVLKFEKPIVAGDKLYCDVYVDSVREAHGTQI  120
			  	121  IVTKNIVTNEEGDLVQETYTTLAGRAGEDGEGFSDGAA

Known structures in the PDB
No Known structures
1 16 31 46 61 76 91 106 121 136 151 Range: 6 to 138  |  Coverage: 83% zf-MaoC Range: 1 to 148  |  Coverage: 93% 1 Range: 1 to 158  |  Coverage: 99% 1
Number of amino acids : 158
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
zf-MaoCPF134526-138
Mtb Structural Proteome models
Model Number1
Model nameRv0635
Template1Q6W    APDBCREDO
Template coverage13_159
Template Identity(%)12.9
Model coverage(%)93.0
Normalized DOPE score0.093

Structure Models from Chopin
Model Number1
Profiled.38.1.4 - 3.10.129.10
Click for model details
zscore14.25
Residue begin1
Residue end158
Binding pockets
STRING
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Protein interacting with Rv0635Gene nameConfidence Score
Rv0636hadB0.998
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions