Rv0526

Tuberculist information
Gene nameRv0526
Protein functionPossible thioredoxin protein (thiol-disulfide interchange protein)
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)616.846
Molecular mass(da)23218.3
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 216
	  		  	1    MQSRATRRSGALTMRRLVIAAAVSALLLTGCSGRDAVAQGGTFEFVSPGGKTDIFYDPPA   60
			  	61   SRGRPGPLSGPELADPARSVSLDDFPGQVVVVNVWGQWCGPCRAEVSQLQRVYDATRGAG  120
			  	121  VSFLGIDVRDNNRQAPQDFINDRHVTYPSIYDPAMRTLIAFGGKYPTSVIPSTLVLDRQH  180
			  	181  RVAAVFLRELLAADLQPVVERVAEEEPSGRAPVGAQ

Known structures in the PDB
No Known structures
1 22 43 64 85 106 127 148 169 190 211 Range: 69 to 185  |  Coverage: 53% AhpC-TSA Range: 29 to 204  |  Coverage: 81% 1 Range: 66 to 209  |  Coverage: 66% 1
Number of amino acids : 216
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
AhpC-TSAPF0057869-185
Mtb Structural Proteome models
Model Number1
Model nameRv0526
Template1JFU    APDBCREDO
Template coverage8_180
Template Identity(%)20.8
Model coverage(%)81.0
Normalized DOPE score-1.058

Structure Models from Chopin
Model Number1
Profilec.47.1.8 - 3.40.30.10
Click for model details
zscore10
Residue begin66
Residue end209
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0526Gene nameConfidence Score
Rv0527ccdA0.998
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
selenomethioninePubChem0.767196.106
SeMetPubChem0.756196.106