Rv0434

Tuberculist information
Gene nameRv0434
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)521.514
Molecular mass(da)23750.3
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 217
	  		  	1    MADFAPVELAMFPLESAPLPDEDLPLHIFEPRYAALVRDCMDTADPRFGVVLISRGREVG   60
			  	61   GGDTRCDVGTLARITECADAGSGRYMLRCRVGERIRVCDWLPDDPYPRAKVRFWPDQPGH  120
			  	121  PVTAAQLLEVEDRVVALFERIAAARGVRLPAREVVLGYPVVDPADTGQRLYALACRVPMG  180
			  	181  PADRYAVLATPSAADRLVRLGDALDSVAAMVEFELST

Known structures in the PDB
No Known structures
1 22 43 64 85 106 127 148 169 190 211 Range: 8 to 206  |  Coverage: 91% LON Range: 8 to 204  |  Coverage: 90% 1 Range: 6 to 114  |  Coverage: 49% 1
Number of amino acids : 217
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
LONPF021908-206
Mtb Structural Proteome models
Model Number1
Model nameRv0434
Template1ZBO    APDBCREDO
Template coverage3_196
Template Identity(%)27.8
Model coverage(%)90.3
Normalized DOPE score-0.469

Structure Models from Chopin
Model Number1
Profileb.122.1.10
Click for model details
zscore14.36
Residue begin6
Residue end114
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0434Gene nameConfidence Score
Rv0433Rv04330.946
Rv0431Rv04310.927
Rv0430Rv04300.92
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions